Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.34 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3849215 | 0.96 | PPARA (0.45) | PPARAPPARGPPARDKCNH2PCSK9 | |
| SCHEMBL3840771 | 0.96 | PPARA (0.45) | PPARAPPARGPPARDKCNH2PCSK9 | |
| SCHEMBL3845277 | 0.96 | PPARA (0.45) | PPARAPPARGPPARDKCNH2PCSK9 | |
| SCHEMBL3842928 | 0.93 | PPARA (0.42) | PPARAPPARGPPARDKCNH2CYP2D6 | |
| SCHEMBL3844859 | 0.93 | PPARA (0.42) | PPARAPPARGPPARDKCNH2CYP2D6 | |
| SCHEMBL3842503 | 0.93 | PPARA (0.52) | PPARAPPARGPPARDKCNH2CYP2D6 | |
| SCHEMBL3844910 | 0.93 | PPARA (0.41) | PPARAPPARGPPARDKCNH2CYP2D6 | |
| SCHEMBL3841464 | 0.92 | PPARA (0.48) | PPARAPPARGPPARDCYP2D6ADORA3 | |
| SCHEMBL3844352 | 0.91 | PPARA (0.48) | PPARAPPARGPPARDCYP2D6ADORA3 | |
| SCHEMBL3851244 | 0.91 | PPARA (0.43) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |