Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 19/20 | 1.00 |
| ▸ | SOAT2 | O75908 | 6/20 | 1.00 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384253 | 1.00 | DGAT1 (1.00) | DGAT1SOAT2SOAT1L3MBTL1CYP2C9 | |
| SCHEMBL10198057 | 1.00 | DGAT1 (1.00) | DGAT1SOAT2SOAT1L3MBTL1CYP2C9 | |
| SCHEMBL409396 | 0.94 | DGAT1 (0.88) | DGAT1SOAT2SOAT1L3MBTL1 | |
| SCHEMBL10260785 | 0.94 | DGAT1 (0.88) | DGAT1SOAT2SOAT1L3MBTL1 | |
| SCHEMBL409397 | 0.94 | DGAT1 (0.88) | DGAT1SOAT2SOAT1L3MBTL1 | |
| SCHEMBL10198330 | 0.93 | DGAT1 (0.87) | DGAT1SOAT2SOAT1L3MBTL1 | |
| SCHEMBL10197410 | 0.92 | DGAT1 (0.85) | DGAT1SOAT2SOAT1L3MBTL1 | |
| SCHEMBL10198189 | 0.91 | DGAT1 (0.84) | DGAT1SOAT2SOAT1CYP2C9DGAT2 | |
| SCHEMBL382280 | 0.91 | DGAT1 (0.84) | DGAT1SOAT2SOAT1CYP2C9DGAT2 | |
| SCHEMBL382279 | 0.91 | DGAT1 (0.84) | DGAT1SOAT2SOAT1CYP2C9DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022057-A1 | BICYCLIC COMPOUNDS AS INHIBITORS OF DIACYGLYCEROL ACYLTRANSFERASE | SCHERING CORPORATION (US) | 2012-01-26 | — | — | US | disclosed |
| EP-2408744-A1 | BICYCLIC COMPOUNDS AS INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | Schering Corporation (US) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010107768-A1 | BICYCLIC COMPOUNDS AS INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | SCHERING CORPORATION (US) | 2010-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022057-A1 | BICYCLIC COMPOUNDS AS INHIBITORS OF DIACYGLYCEROL ACYLTRANSFERASE | DGAT2, DGAT1, LCAT | DGAT1 2/4885SOAT2 9/4885SOAT1 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.