Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844501 | 0.90 | KDM4E (0.35) | LTA4HALDH1A1TP53POLBSMN1; SMN2 | |
| SCHEMBL3840687 | 0.88 | POLB (0.36) | LTA4HALDH1A1TP53POLBSMN1; SMN2 | |
| SCHEMBL3842934 | 0.79 | SLC2A1 (0.38) | MAPK14LMNASMN1; SMN2HTTRAB9A | |
| SCHEMBL3845617 | 0.78 | PPARA (0.42) | — | |
| SCHEMBL3285973 | 0.77 | MAPK14 (0.36) | ALDH1A1MAPK14SMN1; SMN2HTT | |
| SCHEMBL3286654 | 0.76 | MAPK14 (0.38) | ALDH1A1MAPK14SMN1; SMN2HTT | |
| SCHEMBL3284982 | 0.75 | SMPD1 (0.38) | ALDH1A1MAPK14TP53SMN1; SMN2HTT | |
| SCHEMBL3842898 | 0.72 | PDE5A (0.37) | ALDH1A1MAPK14POLBMEN1KMT2A | |
| SCHEMBL3850653 | 0.71 | PPARA (0.39) | ALDH1A1MAPK14POLBMEN1KMT2A | |
| SCHEMBL4912505 | 0.71 | PPARA (0.37) | ALDH1A1MAPK14TP53POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |