Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | HRH2 | P25021 | 3/20 | 0.33 |
| ▸ | HRH1 | P35367 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840686 | 0.89 | MAPK1 (0.34) | SLC2A1L3MBTL1SMN1; SMN2MAPK1PPARG | |
| SCHEMBL3842937 | 0.79 | LTA4H (0.36) | MAPK14SMN1; SMN2LMNAHTTRAB9A | |
| SCHEMBL3845612 | 0.78 | PPARA (0.42) | TSHRPPARGPPARA | |
| SCHEMBL3285973 | 0.78 | MAPK14 (0.36) | MAPK14L3MBTL1ATMNPSR1ALOX5 | |
| SCHEMBL3286654 | 0.78 | MAPK14 (0.38) | MAPK14L3MBTL1NPSR1HRH2HRH1 | |
| SCHEMBL3284982 | 0.76 | SMPD1 (0.38) | MAPK14L3MBTL1ATMNPSR1ALOX5 | |
| SCHEMBL3841065 | 0.72 | PPARA (0.45) | PPARGPPARA | |
| SCHEMBL3844501 | 0.70 | KDM4E (0.35) | SMN1; SMN2MAPK1PPARGPPARA | |
| SCHEMBL3844828 | 0.69 | PPARG (0.36) | MAPK14L3MBTL1NPSR1ALOX5SMN1; SMN2 | |
| SCHEMBL3291240 | 0.69 | PPARA (0.35) | PPARGPPARATHRATHRBSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |