Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840687 | 0.98 | POLB (0.36) | KDM4EGAAALDH1A1CYP2D6MAPK1 | |
| SCHEMBL3842937 | 0.90 | LTA4H (0.36) | KDM4EALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL3840686 | 0.80 | MAPK1 (0.34) | GAACYP2D6MAPK1SMN1; SMN2MAOA | |
| SCHEMBL3284699 | 0.78 | THRA (0.36) | CYP2D6MAOAMAOBPPARGPPARA | |
| SCHEMBL3291240 | 0.78 | PPARA (0.35) | CYP2D6MAOAMAOBPPARGPPARA | |
| SCHEMBL3286825 | 0.76 | PPARA (0.36) | KDM4EALDH1A1SMN1; SMN2MAOAMAOB | |
| SCHEMBL3287365 | 0.76 | PPARA (0.36) | KDM4EALDH1A1SMN1; SMN2MAOAMAOB | |
| SCHEMBL3845617 | 0.74 | PPARA (0.42) | CYP1A2PPARGPPARA | |
| SCHEMBL3292854 | 0.71 | PPARA (0.42) | KDM4EALDH1A1CYP2D6CYP2C19MAOA | |
| SCHEMBL3842934 | 0.70 | SLC2A1 (0.38) | MAPK1SMN1; SMN2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |