Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.55 |
| ▸ | CA2 | P00918 | 10/20 | 0.55 |
| ▸ | CA9 | Q16790 | 8/20 | 0.55 |
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA7 | P43166 | 3/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.55 |
| ▸ | CA3 | P07451 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844382 | 0.98 | CA1 (0.57) | CA1CA2CA9CA12CA7 | |
| SCHEMBL27539096 | 0.98 | CA1 (0.57) | CA1CA2CA9CA12CA7 | |
| SCHEMBL12479668 | 0.98 | CA1 (0.57) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28285245 | 0.96 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| SCHEMBL4799214 | 0.96 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Acetamide SCHEMBL18246548 | 0.87 | CA1 (0.52) | CA1CA2CA9CA12CA7 | |
| SCHEMBL11586756 | 0.87 | CA1 (0.64) | CA1CA2CA9CA12CA7 | |
| SCHEMBL9191350 | 0.87 | CA1 (0.64) | CA1CA2CA9CA12CA7 | |
| SCHEMBL27951777 | 0.85 | CA1 (0.61) | CA1CA2CA9CA12CA7 | |
| SCHEMBL2494632 | 0.84 | CA1 (0.67) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603521-B1 | AUGMENTATION OF PYRITHIONE ACTIVITY OR A POLYVALENT METAL SALT OF PYRITHIONE ACTIVITY BY ZINC-CONTAINING LAYERED MATERIAL | PROCTER & GAMBLE (US) | 2020-06-17 | — | — | EP | disclosed |
| EP-1855645-B1 | DIIODOMETHYL-P-TOLYLSULFONE AS A PARTICULATE DISPERSION IN A LIQUID SOLVENT IN COMBINATION WITH AN ANTI-DANDRUFF ACTIVE | PROCTER & GAMBLE (US) | 2009-11-04 | — | — | EP | disclosed |
| US-20080206355-A1 | Composition comprising a particulate zinc material, a pyrithione or a polyvalent metal salt of a pyrithione and a synthetic cationic polymer | THE PROCTER & GAMBLE COMPANY | 2008-08-28 | — | — | US | disclosed |
| EP-1855645-A2 | DIIODOMETHYL-P-TOLYLSULFONE AS A PARTICULATE DISPERSION IN A LIQUID SOLVENT IN COMBINATION WITH AN ANTI-DANDRUFF ACTIVE | The Procter and Gamble Company (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006083630-A2 | DIIODOMETHYL-P-TOLYLSULFONE AS A PARTICULATE DISPERSION IN A LIQUID SOLVENT IN COMBINATION WITH AN ANTI-DANDRUFF ACTIVE | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060171911-A1 | Diiodomethyl-p-tolylsulfone as a particulate dispersion in a liquid solvent in combination with an anti-dandruff active | PROCTER & GAMBLE COMPANY, THE | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080206355-A1 | Composition comprising a particulate zinc material, a pyrithione or a polyvalent metal salt of a pyrithione and a synthetic cationic polymer | SLC39A3, SLC39A14, SLC30A7 | CA1 268/4885CA2 1059/4885CA9 4263/4885 |
| US-20060171911-A1 | Diiodomethyl-p-tolylsulfone as a particulate dispersion in a liquid solvent in combination with an anti-dandruff active | TST, PIK3C3, ETF1 | CA1 4173/4885CA2 3832/4885CA9 4137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.