Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3847246 | 0.91 | KMT2A (0.40) | PDE2APDE10ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL3861650 | 0.84 | PDE2A (0.41) | PDE2APDE10ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL28028926 | 0.80 | PDE2A (0.38) | PDE2APDE10ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL2348112 | 0.80 | NPC1 (0.41) | PDE2APDE10ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL3844244 | 0.76 | PDE2A (0.36) | PDE2APDE10ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL3846421 | 0.76 | PDE2A (0.36) | PDE2APDE10ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL1870901 | 0.76 | PTGES (0.38) | PDE2APDE10ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL3063136 | 0.76 | PDE2A (0.36) | PDE2APDE10ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL3063953 | 0.76 | KMT2A (0.36) | PDE2APDE10ALMNAKMT2AHPGD | |
| SCHEMBL3570121 | 0.75 | NPC1 (0.47) | SMN1; SMN2LMNAMAPK1HTTPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2042491-A1 | Pyridazines as fungicides | Bayer CropScience AG (DE) | 2009-04-01 | — | — | EP | disclosed |
| EP-2042491-A1 | Pyridazines as fungicides | Bayer CropScience AG (DE) | 2009-04-01 | — | — | EP | disclosed |