Phenol

Phenol

SCHEMBL3843096

C=COC=C.Oc1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.58
CA2 P00918 3/20 0.58
CA9 Q16790 3/20 0.58
CA14 Q9ULX7 3/20 0.58
CA1 P00915 2/20 0.58
CA3 P07451 2/20 0.58
CA4 P22748 2/20 0.58
GLA P06280 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
ESR1 P03372 5/20 0.42
ESR2 Q92731 4/20 0.42
LTA4H P09960 1/20 0.42
NR1H2 P55055 1/20 0.42
BAX Q07812 1/20 0.42
MMP3 P08254 1/20 0.42
BCL2L1 Q07817 1/20 0.42
ALDH1A1 P00352 3/20 0.38
TSHR P16473 1/20 0.38
MEN1 O00255 2/20 0.37
NPC1 O15118 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL473604 0.86 HSD17B10 (0.50) CA12CA2CA9CA14CA1
Resorcinol SCHEMBL4252846 0.82 CA12 (0.60) CA12CA2CA9CA14CA1
Catechol SCHEMBL4263735 0.81 CA2 (0.56) CA12CA2CA14CA1CA3
Phenol SCHEMBL7763305 0.80 CA12 (0.69) CA12CA2CA9CA14CA1
Phenol SCHEMBL5469697 0.80 CA12 (0.69) CA12CA2CA9CA14CA1
Phenol SCHEMBL429762 0.80 CA12 (0.69) CA12CA2CA9CA14CA1
Biphenyl SCHEMBL2586794 0.78 ALDH1A1 (0.53) TDP1MMP3BCL2L1ALDH1A1TSHR
Phenol SCHEMBL7070848 0.78 CA12 (0.65) CA12CA2CA9CA14CA1
Phenol SCHEMBL258238 0.78 CA12 (0.65) CA12CA2CA9CA14CA1
Phenol SCHEMBL9065311 0.78 CA12 (0.65) CA12CA2CA9CA14CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4353520-A None JP disclosed
CN-104220536-B Resin composition for coating paint 三菱化学株式会社 2017-06-27 CN disclosed
CN-106349792-A Rust-proof turbine blade 南京赛达机械制造有限公司 2017-01-25 CN disclosed
CN-103012129-B Calixarene compound and photoresist composition comprising the same ROHM & HAAS ELECT MAT 2015-07-01 CN disclosed
EP-2039509-B1 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORP (JP) 2014-03-26 EP disclosed
CN-103012129-A Calixarene compound and photoresist composition comprising the same DOW GLOBAL TECHNOLOGIES LLC 2013-04-03 CN disclosed
CN-101208069-B Hydrophilized curable silicone impression materials with improved storage behavior 3M INNOVATIVE PROPERTIES CO 2012-05-02 CN disclosed
US-7629494-B2 Process for producing cyclopropylphenol derivative MITSUI CHEMICALS AGRO, INC. (JP) 2009-12-08 US disclosed
EP-2039509-A1 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM Corporation (JP) 2009-03-25 EP disclosed
US-20090054681-A1 Production Process of cyclopropylphenol derivatives SANKYO AGRO COMPANY, LIMITED (JP) 2009-02-26 US disclosed
CN-101208069-A Hydrophilized curable silicone impression materials with improved storage behavior 3M INNOVATIVE PROPERTIES CO (US) 2008-06-25 CN disclosed
EP-1880987-A1 PROCESS FOR PRODUCING CYCLOPROPYLPHENOL DERIVATIVE Sankyo Agro Company, Limited (JP) 2008-01-23 EP disclosed
JP-H04353520-A POLYMERIC DIPHYENYLDIAMINE GOODYEAR TIRE & RUBBER CO:THE 1992-12-08 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054681-A1 Production Process of cyclopropylphenol derivatives CBR3, CYP4X1, CYP4A11 CA12 606/4885CA2 65/4885CA9 223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.