Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | RAF1 | P04049 | 18/20 | 0.34 |
| ▸ | BRAF | P15056 | 10/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3770601 | 0.91 | CCNT1 (0.34) | RAF1BRAF | |
| SCHEMBL3772521 | 0.83 | ABL1 (0.38) | ABL1RAF1 | |
| SCHEMBL3772476 | 0.81 | ABL1 (0.35) | ABL1 | |
| SCHEMBL3778331 | 0.81 | SYK (0.31) | — | |
| SCHEMBL3773171 | 0.79 | AR (0.38) | — | |
| SCHEMBL3147365 | 0.78 | ABL1 (0.37) | ABL1RAF1BRAF | |
| SCHEMBL3843144 | 0.77 | ABL1 (0.34) | ABL1RAF1BRAF | |
| SCHEMBL3147370 | 0.76 | ABL1 (0.36) | ABL1RAF1BRAF | |
| SCHEMBL3781398 | 0.76 | FFAR4 (0.35) | ABL1 | |
| SCHEMBL3765793 | 0.75 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317698-A1 | Polysubstituted Pyridinylaminoalkylene- and Pyridinyloxyalkylene-Cyclopropanamine Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them | LES LABORATOIRES SERVIER (FR) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317698-A1 | Polysubstituted Pyridinylaminoalkylene- and Pyridinyloxyalkylene-Cyclopropanamine Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them | CHRNA6, CHRNE, CHRNG | ABL1 1469/4885RAF1 2398/4885BRAF 2473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.