Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3822795 | 0.85 | BRD4 (0.61) | BRD4SMN1; SMN2ACACBKMT2AHPGD | |
| SCHEMBL3843203 | 0.81 | POLB (0.59) | BRD4KMT2AHPGDP2RX7ALDH1A1 | |
| SCHEMBL3823547 | 0.80 | BRD4 (0.51) | BRD4SMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL30282498 | 0.80 | BRD4 (0.67) | BRD4SMN1; SMN2KMT2AHPGDALDH1A1 | |
| SCHEMBL28956225 | 0.80 | BRD4 (0.67) | BRD4SMN1; SMN2KMT2AHPGDALDH1A1 | |
| SCHEMBL12667142 | 0.80 | BRD4 (0.67) | BRD4SMN1; SMN2KMT2AHPGDALDH1A1 | |
| SCHEMBL1362127 | 0.77 | BRD4 (0.63) | BRD4SMN1; SMN2KMT2AHPGDP2RX7 | |
| SCHEMBL15042223 | 0.77 | BRD4 (0.63) | BRD4SMN1; SMN2KMT2AHPGDP2RX7 | |
| SCHEMBL3821889 | 0.77 | BRD4 (0.51) | BRD4SMN1; SMN2KMT2AHPGDHTT | |
| SCHEMBL3844849 | 0.77 | MEN1 (0.40) | KMT2AALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2028247-A1 | Use of 1-alkyl-5-oxo-pyrrolidine-3-carbolic acid esters as gas hydrate inhibitors with improved biological degradability | CLARIANT INTERNATIONAL LTD. (CH) | 2009-02-25 | — | — | EP | disclosed |