Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 2/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825321 | 0.90 | MEN1 (0.47) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3825328 | 0.90 | MEN1 (0.47) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3823823 | 0.89 | MEN1 (0.40) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3823832 | 0.89 | MEN1 (0.40) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL1361571 | 0.84 | L3MBTL1 (0.42) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3829072 | 0.83 | DGKA (0.47) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3828270 | 0.82 | ALDH1A1 (0.43) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3829040 | 0.81 | ALDH1A1 (0.42) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL8154312 | 0.81 | L3MBTL1 (0.43) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL15041986 | 0.80 | KMT2A (0.51) | MEN1CYP2C19KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2028247-A1 | Use of 1-alkyl-5-oxo-pyrrolidine-3-carbolic acid esters as gas hydrate inhibitors with improved biological degradability | CLARIANT INTERNATIONAL LTD. (CH) | 2009-02-25 | — | — | EP | disclosed |