2-Picolinic Acid

2-Picolinic Acid

SCHEMBL3843691

O=C(O)c1ccccn1.[Na]

nearest known ligand 0.95

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.95
▸ L3MBTL1 Q9Y468 2/20 0.95
▸ NAPRT Q6XQN6 1/20 0.95
▸ P4HTM Q9NXG6 1/20 0.95
▸ CES2 O00748 1/20 0.67
▸ CES1 P23141 1/20 0.67
▸ KMT2A Q03164 2/20 0.63
▸ ALDH1A1 P00352 2/20 0.61
▸ GSK3B P49841 1/20 0.55
▸ PTGS2 P35354 1/20 0.55
▸ KDM4E B2RXH2 4/20 0.53
▸ NPC1 O15118 3/20 0.53
▸ RAB9A P51151 3/20 0.53
▸ MAPT P10636 2/20 0.53
▸ PKM P14618 2/20 0.53
▸ TDP1 Q9NUW8 2/20 0.52
▸ ALOX15 P16050 1/20 0.52
▸ TSHR P16473 1/20 0.52
▸ ACMSD Q8TDX5 1/20 0.52
▸ CTNNB1 P35222 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Picolinic Acid SCHEMBL29368665 0.98 — —
2-Picolinic Acid SCHEMBL28737810 0.98 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL674837 0.98 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL7457912 0.98 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL36055 0.98 — —
2-Picolinic Acid SCHEMBL5203401 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL15401824 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL5058097 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL22835776 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL20721125 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119193573-A Screening method of selenium-enriched saccharomycetes 安琪酵母股份有限公司 2024-12-27 — — CN claimed
CN-105848627-A Lip composition in the form of an inverse emulsion comprising a humectant, and treatment process using the same 莱雅公司 2016-08-10 — — CN claimed
CN-1772737-A Synthesis process of chronium 2-picolinate SHANXI COAL CHEM INST (CN) 2006-05-17 — — CN claimed
CN-119193573-A Screening method of selenium-enriched saccharomycetes 安琪酵母股份有限公司 2024-12-27 — — CN disclosed
CN-109942600-A A kind of preparation method of Yi Dushaban 内蒙古京东药业有限公司 2019-06-28 — — CN disclosed
CN-104736136-B Beauty and make-up is used or medicinal moisturizing ingredient 巴斯夫美容护理法国公司 2019-02-15 — — CN disclosed
CN-108472202-A Cosmetic composition comprising ceramide and cholesterol 莱雅公司 2018-08-31 — — CN disclosed
CN-108366924-A Cosmetic composition comprising a specific filler combination and a film-forming polymer to improve long-lasting effect 莱雅公司 2018-08-03 — — CN disclosed
CN-107787221-A Include the aqueous cosmetic composition of alkylcellulose, at least one nonvolatile oil and resin based on hydrocarbon 莱雅公司 2018-03-09 — — CN disclosed
CN-105008358-B inhibitors of human immunodeficiency virus replication 百时美施贵宝公司 2017-12-29 — — CN disclosed
CN-107375019-A AQUEOUS COSMETIC COMPOSITION COMPRISING ALKYLCELLULOSE 欧莱雅 2017-11-24 — — CN disclosed
CN-101099715-B Cosmetic compositions combining a C-glycoside derivative and an N-acylamino amide derivative OU LAIYA 2012-09-05 — — CN disclosed
CN-102223924-A Photoprotective composition containing an unmodified gelling starch and polyamide particles OREAL 2011-10-19 — — CN disclosed
CN-101810543-A Cosmetic composition and a light stabilizing method thereof OLIER CHEMISTRY INDUSTRY CO LTD 2010-08-25 — — CN disclosed
EP-2099796-A1 AZA-INDOLYL COMPOUNDS AND METHODS OF USE Genentech, Inc. (US) 2009-09-16 — — EP disclosed
WO-2008067481-A1 AZA-INDOLYL COMPOUNDS AND METHODS OF USE GENENTECH, INC. (US) 2008-06-05 — — WO disclosed
CN-101099715-A Cosmetic compositions combining a C-glycoside derivative and an N-acylamino amide derivative OREAL (FR) 2008-01-09 — — CN disclosed
CN-1772737-A Synthesis process of chronium 2-picolinate SHANXI COAL CHEM INST (CN) 2006-05-17 — — CN disclosed
EP-1586578-A2 Method of removing allyl series protecting group using novel ruthenium complex and method of synthesizing allyl ethers NAGOYA UNIVERSITY (JP) 2005-10-19 — — EP disclosed
US-20050203317-A1 Method of removing allyl series protecting group using novel ruthenium complex and method of synthesizing allyl ethers NAGOYA UNIVERSITY, A NATIONAL UNIV. CORP. OF JP (JP) 2005-09-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050203317-A1 Method of removing allyl series protecting group using novel ruthenium complex and method of synthesizing allyl ethers AP2M1, AP3M1, AP2A2 LMNA 2713/4885L3MBTL1 2694/4885NAPRT 4376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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