Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1738363 | 0.99 | KMT2A (0.42) | MEN1KMT2APSMB1CYP1A2CYP3A4 | |
| SCHEMBL3843518 | 0.89 | CYP1A2 (0.47) | MEN1KMT2APSMB1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL1736574 | 0.88 | CYP1A2 (0.46) | MEN1KMT2APSMB1CYP1A2CYP3A4 | |
| SCHEMBL2480169 | 0.86 | CYP3A4 (0.47) | MEN1KMT2APSMB1CYP3A4UTS2R | |
| Hydrochloric Acid SCHEMBL1737704 | 0.85 | MAPK1 (0.46) | MEN1KMT2APSMB1CYP3A4UTS2R | |
| SCHEMBL3843126 | 0.83 | MEN1 (0.45) | MEN1KMT2APSMB1CYP1A2CYP3A4 | |
| SCHEMBL3846867 | 0.83 | KMT2A (0.46) | MEN1KMT2APSMB1UTS2RHTT | |
| Hydrochloric Acid SCHEMBL1737814 | 0.82 | KMT2A (0.44) | MEN1KMT2APSMB1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL1738613 | 0.82 | FABP4 (0.47) | MEN1KMT2AUTS2RHTTNPC1 | |
| Hydrochloric Acid SCHEMBL1737311 | 0.82 | MEN1 (0.50) | MEN1KMT2AUTS2RHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-A4 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2009-09-09 | — | — | EP | claimed |
| JP-2008511621-A | — | — | 2008-04-17 | — | — | JP | claimed |
| EP-1784404-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | claimed |
| WO-2006025716-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |