Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 3/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1738388 | 0.99 | KMT2A (0.45) | KMT2ARAB9AADRA2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL1735367 | 0.88 | KMT2A (0.43) | KMT2ARAB9AMEN1MAPTADORA3 | |
| SCHEMBL2480169 | 0.87 | CYP3A4 (0.47) | KMT2AMEN1ADORA1UTS2RKDM4E | |
| Hydrochloric Acid SCHEMBL1737704 | 0.86 | MAPK1 (0.46) | KMT2AMEN1ADORA1UTS2RKDM4E | |
| SCHEMBL3843126 | 0.84 | MEN1 (0.45) | KMT2ARAB9AMEN1UTS2RKDM4E | |
| Hydrochloric Acid SCHEMBL1738613 | 0.83 | FABP4 (0.47) | KMT2ARAB9AMEN1MAPTUTS2R | |
| Hydrochloric Acid SCHEMBL1737814 | 0.83 | KMT2A (0.44) | KMT2ARAB9AMEN1MAPTUTS2R | |
| SCHEMBL3843694 | 0.83 | MEN1 (0.43) | KMT2ARAB9AMEN1MAPTCDK1 | |
| Hydrochloric Acid SCHEMBL1737311 | 0.83 | MEN1 (0.50) | KMT2ARAB9AMEN1ADORA3ADORA1 | |
| Hydrochloric Acid SCHEMBL1738363 | 0.82 | KMT2A (0.42) | KMT2ARAB9AMEN1MAPTUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-A4 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2009-09-09 | — | — | EP | claimed |
| JP-2008511621-A | — | — | 2008-04-17 | — | — | JP | claimed |
| EP-1784404-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | claimed |
| WO-2006025716-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |