Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.43 |
| ▸ | PPARG | P37231 | 13/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841077 | 0.95 | PPARA (0.46) | PPARAPPARGPPARDS1PR4S1PR1 | |
| SCHEMBL3849260 | 0.92 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL3843706 | 0.91 | PPARA (0.44) | PPARAPPARGPPARD | |
| SCHEMBL3849934 | 0.91 | PPARG (0.38) | PPARAPPARGS1PR1S1PR3 | |
| SCHEMBL3842635 | 0.89 | PPARA (0.47) | PPARAPPARGPPARDAGTR1 | |
| SCHEMBL3840362 | 0.89 | PPARA (0.43) | PPARAPPARGPPARDS1PR4S1PR1 | |
| SCHEMBL3841221 | 0.88 | PPARA (0.41) | PPARAPPARGPPARDS1PR4S1PR1 | |
| SCHEMBL3849215 | 0.88 | PPARA (0.45) | PPARAPPARGPPARD | |
| SCHEMBL3841459 | 0.87 | PKM (0.34) | PPARAPPARGPPARD | |
| SCHEMBL3285183 | 0.87 | PPARA (0.42) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |