SCHEMBL3843977

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4490509	0.93	POLB (0.52)	POLBALDH1A1KDM4EMAPTLMNA
	SCHEMBL3846015	0.92	DRD2 (0.57)	POLBALDH1A1KDM4EMAPTLMNA
	SCHEMBL3870455	0.90	DRD2 (0.50)	POLBALDH1A1KDM4EMAPTLMNA
	SCHEMBL3844108	0.90	HTR2A (0.58)	POLBALDH1A1KDM4EDRD2DRD3
	SCHEMBL3853473	0.90	ALDH1A1 (0.56)	POLBALDH1A1KDM4EMAPTLMNA
	Hydrochloric Acid SCHEMBL3844588	0.89	MAPT (0.61)	POLBALDH1A1KDM4EMAPTLMNA
	SCHEMBL3845743	0.89	ALDH1A1 (0.58)	POLBALDH1A1KDM4EMAPTLMNA
	SCHEMBL3845062	0.89	DRD2 (0.52)	POLBALDH1A1KDM4EMAPTLMNA
	SCHEMBL3866800	0.88	DRD2 (0.61)	POLBALDH1A1KDM4EMAPTLMNA
	SCHEMBL13637865	0.88	ALDH1A1 (0.56)	POLBALDH1A1KDM4EMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.