SCHEMBL384449

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20347945	0.86	KDM4E (0.44)	L3MBTL1TRPV1ALDH1A1MAPTATM
	SCHEMBL12126027	0.86	CYP1A2 (0.51)	L3MBTL1IDO1ALDH1A1HSD17B10PDE2A
	SCHEMBL4008713	0.84	IDO1 (0.47)	L3MBTL1IDO1LMNAMAPTATM
	SCHEMBL385394	0.83	L3MBTL1 (0.43)	L3MBTL1TRPV1ALDH1A1HSD17B10PTGDR2
	SCHEMBL10107216	0.81	ESR1 (0.44)	L3MBTL1ALDH1A1HSD17B10PTGDR2PPARG
	SCHEMBL14471138	0.81	PPARG (0.51)	L3MBTL1ALDH1A1HSD17B10PTGDR2PPARG
	SCHEMBL10183560	0.80	L3MBTL1 (0.41)	L3MBTL1TRPV1ALDH1A1HSD17B10PTGDR2
	SCHEMBL12244251	0.80	L3MBTL1 (0.44)	L3MBTL1IDO1ALDH1A1HSD17B10PDE2A
	SCHEMBL10107044	0.79	IDO1 (0.42)	L3MBTL1IDO1ALDH1A1HSD17B10PDE2A
	SCHEMBL27550496	0.79	IDO1 (0.40)	L3MBTL1IDO1ALDH1A1HSD17B10PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.