SCHEMBL385394

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL384449	0.83	L3MBTL1 (0.43)	L3MBTL1ALDH1A1HSD17B10PTGDR2MAPT
	SCHEMBL10107216	0.81	ESR1 (0.44)	L3MBTL1ALDH1A1HSD17B10PTGDR2LMNA
	SCHEMBL14471138	0.81	PPARG (0.51)	L3MBTL1ALDH1A1HSD17B10PTGDR2KDM4E
	SCHEMBL10183560	0.80	L3MBTL1 (0.41)	L3MBTL1ALDH1A1HSD17B10PTGDR2MAPT
	SCHEMBL10352193	0.78	L3MBTL1 (0.60)	L3MBTL1ALDH1A1HSD17B10PTGDR2MAPT
	SCHEMBL955509	0.78	CYP1A1 (0.46)	L3MBTL1ALDH1A1HSD17B10PTGDR2MAPT
	SCHEMBL16433627	0.77	MAPT (0.46)	L3MBTL1ALDH1A1MAPTATMKDM4E
	SCHEMBL957682	0.76	KDM4E (0.62)	ALDH1A1HSD17B10PTGDR2KDM4EHPGD
	SCHEMBL23665186	0.76	L3MBTL1 (0.43)	L3MBTL1ALDH1A1HSD17B10PTGDR2MAPT
	SCHEMBL16951778	0.76	SCN8A (0.46)	L3MBTL1ALDH1A1HSD17B10PTGDR2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.