SCHEMBL3844567

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3846435	0.89	DRD2 (0.44)	DRD2DRD3HTR1ADRD4HTR2B
	SCHEMBL3849428	0.88	CHRM4 (0.43)	DRD2DRD3HTR1ADRD4HTR2B
	SCHEMBL3846127	0.86	CHRM4 (0.48)	DRD2DRD3CHRM4
	SCHEMBL3845815	0.83	DRD2 (0.50)	DRD2DRD3HTR1ADRD4HTR2B
	SCHEMBL4490457	0.83	CHRM4 (0.47)	DRD2DRD3HTR1ADRD4HTR2B
	SCHEMBL3845209	0.83	DRD2 (0.46)	DRD2DRD3HTR1ADRD4HTR2B
	SCHEMBL3844840	0.83	ADRA1B (0.47)	DRD2DRD3HTR1ACHRM4HTR2A
	SCHEMBL3846859	0.83	DRD2 (0.41)	DRD2DRD3HTR1ADRD4HTR2B
	SCHEMBL3851246	0.83	KDM4E (0.55)	CHRM4MAPT
	SCHEMBL3849328	0.82	DRD2 (0.45)	DRD2DRD3CACNA1IMAPTDRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.