Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
| ▸ | MPL | P40238 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843507 | 0.82 | CHRNA7 (0.51) | CHRNA7KDM1AMPL | |
| SCHEMBL3841705 | 0.82 | CHRNA7 (0.61) | CHRNA7KDM1A | |
| SCHEMBL3843503 | 0.82 | CHRNA7 (0.51) | CHRNA7KDM1AMPL | |
| SCHEMBL3841703 | 0.82 | CHRNA7 (0.61) | CHRNA7KDM1A | |
| SCHEMBL3206972 | 0.77 | LSS (0.53) | CHRNA7LSS | |
| SCHEMBL3206963 | 0.77 | LSS (0.53) | CHRNA7LSS | |
| Hydrochloric Acid SCHEMBL9469873 | 0.75 | LSS (0.52) | CHRNA7LSS | |
| SCHEMBL3839996 | 0.73 | CHRNA7 (0.67) | CHRNA7LSS | |
| SCHEMBL3840558 | 0.73 | CHRNA7 (0.61) | CHRNA7LSS | |
| SCHEMBL3840559 | 0.73 | CHRNA7 (0.61) | CHRNA7LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537104-B1 | AZA-BICYCLOALKYL ETHERS AND THEIR USE AS ALPHA7-NACHR AGONISTS | NOVARTIS AG (CH) | 2009-11-11 | — | — | EP | disclosed |