SCHEMBL3844670

SCHEMBL3844670

CCN(CCC[Si](OC)(OC)OC)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA9 Q16790 2/20 0.36
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
LMNA P02545 4/20 0.33
MAPT P10636 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
ALDH1A1 P00352 1/20 0.30
ALDH2 P05091 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5916611 0.95 CA12 (0.35) CA12CA1CA9CYP1A2CYP3A4
SCHEMBL5916965 0.93 LMNA (0.35) CA12CA1CA9CYP1A2CYP3A4
SCHEMBL5916711 0.93 LMNA (0.35) CA12CA1CA9CYP1A2CYP3A4
SCHEMBL9194761 0.90 LMNA (0.32) LMNA
SCHEMBL5916969 0.89 LMNA (0.32) CA12CA1CA9CYP1A2LMNA
SCHEMBL5916618 0.89 CA12 (0.32) CA12CA1CA9
SCHEMBL28036930 0.87 LMNA (0.36) CA12CA1CA9CYP1A2CYP3A4
SCHEMBL5916505 0.86 CA12 (0.33) CA12CA1CA9CYP1A2CYP3A4
SCHEMBL9452183 0.85 LMNA (0.32) LMNA
SCHEMBL443029 0.84 LMNA (0.36) CA12CA1CA9CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937697-B1 METHOD FOR PRODUCTION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-16 EP claimed
EP-1869058-B1 PROCESS FOR MAKING SILYLISOCYANURATE MOMENTIVE PERFORMANCE MAT INC (US) 2009-12-16 EP claimed
EP-1885731-B1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE MOMENTIVE PERFORMANCE MAT INC (US) 2009-11-11 EP claimed
US-20060247407-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) 2006-11-02 US disclosed
US-7057001-B2 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-06-06 US disclosed
US-20050260401-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL AG & CO. KGAA (DE) 2005-11-24 US disclosed
EP-1328586-A1 POLYMERS WITH UREA GROUPS AND SILYL GROUPS AND PRODUCTION AND USE THEREOF Henkel Kommanditgesellschaft auf Aktien (DE) 2003-07-23 EP disclosed
WO-2002050020-A1 METHOD FOR PRODUCING ISOCYANATES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-06-27 WO disclosed
WO-2002034838-A1 POLYMERS WITH UREA GROUPS AND SILYL GROUPS AND PRODUCTION AND USE THEREOF HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-05-02 WO disclosed