Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194761 | 0.93 | LMNA (0.32) | LMNA | |
| SCHEMBL3844670 | 0.87 | CA12 (0.36) | LMNACA12CA9CA1ALDH1A1 | |
| SCHEMBL9452183 | 0.87 | LMNA (0.32) | LMNA | |
| SCHEMBL22477356 | 0.86 | LMNA (0.36) | LMNACA12CA9CA2CA1 | |
| SCHEMBL28036839 | 0.84 | CA12 (0.34) | CA12CA9CA2CA1TSHR | |
| SCHEMBL17732605 | 0.84 | ACHE (0.30) | — | |
| SCHEMBL27989980 | 0.83 | CA12 (0.39) | LMNACA12CA9CA2CA1 | |
| SCHEMBL5916611 | 0.82 | CA12 (0.35) | LMNACA12CA9CA1HPGD | |
| SCHEMBL3796353 | 0.82 | ZDHHC20 (0.43) | LMNALPAR1LPAR5 | |
| SCHEMBL5916965 | 0.81 | LMNA (0.35) | LMNACA12CA9CA1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105121012-B | For preparing the composition of silastic material | 阿绍尼特罗开米有限公司 | 2018-04-03 | — | — | CN | disclosed |
| CN-105026040-B | Composition for preparing silicone rubber material | 阿绍尼特罗开米有限公司 | 2017-10-13 | — | — | CN | disclosed |
| CN-105121012-A | Composition for the production of silicone rubber compositions | NITROCHEMIE GMBH | 2015-12-02 | — | — | CN | disclosed |
| CN-105026040-A | Composition for preparing silicone rubber material | NITROCHEMIE GMBH | 2015-11-04 | — | — | CN | disclosed |