Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.34 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3846159 | 0.98 | GGPS1 (0.36) | PPARGPPARAKMT2AALDH1A1NPC1 | |
| SCHEMBL3844604 | 0.91 | KMT2A (0.36) | PPARGPPARAKMT2AALDH1A1NPC1 | |
| SCHEMBL3842108 | 0.89 | PPARA (0.38) | PPARGPPARAKMT2AALDH1A1MEN1 | |
| SCHEMBL3844116 | 0.89 | PLA2G4B (0.38) | PPARGPPARAKMT2AALDH1A1NPC1 | |
| SCHEMBL3841033 | 0.88 | SMPD1 (0.38) | KMT2AMEN1MAPTHTTSMPD1 | |
| SCHEMBL3286825 | 0.85 | PPARA (0.36) | PPARGPPARAKMT2AALDH1A1NPC1 | |
| SCHEMBL3845248 | 0.84 | PLA2G4B (0.40) | PPARGPPARAKMT2AALDH1A1NPC1 | |
| SCHEMBL3287365 | 0.84 | PPARA (0.36) | PPARGPPARAKMT2AALDH1A1MEN1 | |
| SCHEMBL3846291 | 0.83 | PLA2G4B (0.40) | PPARGPPARAKMT2AALDH1A1NPC1 | |
| SCHEMBL3841370 | 0.83 | PPARA (0.48) | PPARGPPARAKMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |