Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3851781 | 0.84 | TRPV3 (0.34) | TP53KDM4EKCNA5KCNE1SLC6A2 | |
| SCHEMBL3849156 | 0.83 | IDH1 (0.35) | TP53KDM4EKCNA5TSHRKCNE1 | |
| SCHEMBL3844520 | 0.82 | KDM4E (0.34) | TP53KDM4EKCNA5KCNE1SLC6A2 | |
| SCHEMBL3845006 | 0.80 | TSHR (0.36) | TP53KDM4EKCNA5TSHRKCNE1 | |
| SCHEMBL3849158 | 0.75 | TP53 (0.34) | TP53KDM4EKCNA5TSHRKCNE1 | |
| SCHEMBL27563049 | 0.61 | — | — | |
| SCHEMBL507506 | 0.61 | — | — | |
| SCHEMBL2584363 | 0.61 | — | — | |
| SCHEMBL29609775 | 0.61 | — | — | |
| SCHEMBL1193974 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010550-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007122139-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-11-01 | — | — | WO | disclosed |