Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844967 | 0.82 | TP53 (0.35) | KDM4ESLC6A2SLC6A4SLC6A3TP53 | |
| SCHEMBL3851781 | 0.82 | TRPV3 (0.34) | KDM4ESLC6A2SLC6A4SLC6A3TP53 | |
| SCHEMBL3849156 | 0.79 | IDH1 (0.35) | KDM4ETP53KCNA5KCNE1 | |
| SCHEMBL3845006 | 0.75 | TSHR (0.36) | KDM4ESLC6A2SLC6A4SLC6A3TP53 | |
| SCHEMBL3347444 | 0.73 | MAP1LC3B (0.37) | KDM4EPDCD1CD274 | |
| SCHEMBL3849158 | 0.68 | TP53 (0.34) | KDM4ESLC6A2SLC6A4SLC6A3TP53 | |
| SCHEMBL3982745 | 0.60 | ALDH1A1 (0.47) | KDM4E | |
| SCHEMBL9777431 | 0.59 | SLC6A2 (0.54) | KDM4ESLC6A2SLC6A4SLC6A3TP53 | |
| SCHEMBL29864658 | 0.59 | MAPT (0.55) | KDM4ESLC6A2SLC6A4SLC6A3TP53 | |
| SCHEMBL3048607 | 0.59 | MAPT (0.55) | KDM4ESLC6A2SLC6A4SLC6A3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010550-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007122139-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-11-01 | — | — | WO | disclosed |