SCHEMBL3845174

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3844428	0.92	DRD2 (0.70)	DRD2DRD3DRD4HTR1AADRA2A
	SCHEMBL3848634	0.91	DRD2 (0.58)	DRD2DRD3DRD4HTR1AADRA2A
	SCHEMBL3845537	0.90	DRD2 (0.57)	DRD2DRD3DRD4HTR1AADRA2A
	SCHEMBL14347037	0.90	DRD2 (0.57)	DRD2DRD3DRD4HTR1AADRA2A
	SCHEMBL3843708	0.88	DRD2 (0.56)	DRD2DRD3DRD4HTR1AADRA2A
	SCHEMBL3853618	0.88	DRD2 (0.53)	DRD2DRD3DRD4HTR1AHTR2A
	SCHEMBL3863328	0.88	DRD2 (0.57)	DRD2DRD3HTR7ADRA1AADRA1D
	SCHEMBL3846460	0.87	ADRA1B (0.50)	DRD2DRD3HTR1AADRA1AADRA1D
	SCHEMBL3852900	0.87	DRD2 (0.54)	DRD2DRD3DRD4HTR1AADRA2A
	SCHEMBL14346902	0.87	DRD2 (0.47)	DRD2DRD3DRD4HTR1AADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.