SCHEMBL3845181

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3849883	0.90	DRD3 (0.50)	DRD2DRD3POLBHTR7HTR1A
	SCHEMBL3866840	0.88	DRD2 (0.56)	DRD2DRD3POLBHTR7HTR1A
	SCHEMBL3865455	0.87	DRD2 (0.55)	DRD2DRD3POLBHTR7HTR1A
	SCHEMBL4484259	0.85	DRD2 (0.52)	DRD2DRD3POLBHTR7HTR1A
	SCHEMBL3863133	0.83	ALDH1A1 (0.52)	DRD2DRD3HTR7HTR1AHTR2A
	SCHEMBL3849176	0.82	DRD2 (0.58)	DRD2DRD3POLBHTR7HTR1A
	SCHEMBL14346782	0.82	DRD2 (0.58)	DRD2DRD3POLBHTR7HTR1A
	SCHEMBL13630151	0.82	DRD2 (0.58)	DRD2DRD3POLBHTR7HTR1A
	SCHEMBL4493085	0.82	DRD2 (0.49)	DRD2DRD3POLBHTR7HTR1A
	SCHEMBL3844577	0.81	DRD2 (0.62)	DRD2DRD3HTR7HTR1AHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.