SCHEMBL3845593

SCHEMBL3845593

Oc1ccc(C23CC4CC(CC(C4)C2C2C4CC5CC(C4)CC2(c2ccc(O)cc2O)C5)C3)c(O)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.39
ALOX5AP P20292 1/20 0.38
CNR2 P34972 2/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
GAA P10253 3/20 0.37
POLB P06746 1/20 0.37
GFER P55789 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
ESR1 P03372 1/20 0.35
CYP2C9 P11712 1/20 0.35
ESR2 Q92731 1/20 0.35
MAPT P10636 2/20 0.34
XBP1 P17861 1/20 0.34
FAAH O00519 1/20 0.33
P2RX7 Q99572 1/20 0.33
RARB P10826 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28347088 0.84 HSP90AA1 (0.37) HSP90AA1ALOX5APCNR2MEN1KMT2A
SCHEMBL3846317 0.80 GAA (0.45) HSP90AA1CNR2MEN1KMT2AGAA
SCHEMBL2420330 0.78 MEN1 (0.50) HSP90AA1CNR2MEN1KMT2AGAA
SCHEMBL3896937 0.76 CNR2 (0.35) HSP90AA1ALOX5APCNR2MEN1KMT2A
SCHEMBL2426368 0.71 KMT2A (0.43) HSP90AA1ALOX5APCNR2MEN1KMT2A
Formic Acid SCHEMBL28092830 0.71 RARB (0.44) HSP90AA1CNR2MEN1KMT2AGAA
SCHEMBL3756901 0.69 ALOX5AP (0.41) HSP90AA1ALOX5APCNR2MEN1KMT2A
SCHEMBL3846906 0.68 MEN1 (0.41) HSP90AA1ALOX5APCNR2MEN1KMT2A
SCHEMBL3845041 0.68 KMT2A (0.40) HSP90AA1ALOX5APCNR2MEN1KMT2A
SCHEMBL3759906 0.67 CNR2 (0.38) HSP90AA1ALOX5APCNR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed