SCHEMBL2420330

SCHEMBL2420330

Oc1ccc(C23CC4CC(CC(C4)C2)C3)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
GFER P55789 1/20 0.50
CNR2 P34972 1/20 0.47
THRB P10828 1/20 0.43
RECQL P46063 1/20 0.43
NR2E1 Q9Y466 1/20 0.43
HSP90AA1 P07900 1/20 0.43
RARB P10826 5/20 0.43
RARA P10276 3/20 0.42
RARG P13631 3/20 0.42
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL28092830 0.92 RARB (0.44) MEN1KMT2APOLBGAAGFER
SCHEMBL2426368 0.89 KMT2A (0.43) MEN1KMT2APOLBGAAGFER
SCHEMBL3755595 0.85 MEN1 (0.55) MEN1KMT2APOLBGAAGFER
SCHEMBL3759906 0.85 CNR2 (0.38) MEN1KMT2APOLBGAAGFER
SCHEMBL3845041 0.84 KMT2A (0.40) MEN1KMT2APOLBGAAGFER
SCHEMBL3846906 0.84 MEN1 (0.41) MEN1KMT2APOLBGAAGFER
SCHEMBL548708 0.83 MEN1 (0.73) MEN1KMT2APOLBGAAGFER
SCHEMBL11702433 0.81 CNR2 (0.51) MEN1KMT2APOLBGAAGFER
SCHEMBL8024133 0.81 MEN1 (0.43) MEN1KMT2APOLBGAAGFER
SCHEMBL6033366 0.81 MEN1 (0.47) MEN1KMT2APOLBGAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101693764-B Star adamantyl polysulfone and synthetic method thereof UNIV SOUTH CHINA TECH 2011-09-07 CN claimed
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed
CN-107108782-A Terminal-modified soluble polyfunctional vinyl aromatic co-polymer, curable resin composition and use its light guide wave duct 新日铁住金化学株式会社 2017-08-29 CN disclosed
EP-2000510-B1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM SUMITOMO BAKELITE CO (JP) 2012-05-02 EP disclosed
US-8084650-B2 Adamantane derivative, resin composition containing same, and optoelectronic member and sealing agent for electronic circuit using those IDEMITSU KOSAN CO., LTD. (JP) 2011-12-27 US disclosed
US-8017800-B2 Adamantyl group-containing epoxy-modified (meth)acrylate and resin composition containing the same IDEMITSU KOSAN CO., LTD. (JP) 2011-09-13 US disclosed
CN-101693764-B Star adamantyl polysulfone and synthetic method thereof UNIV SOUTH CHINA TECH 2011-09-07 CN disclosed
US-7863347-B2 Resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2011-01-04 US disclosed
US-20100298491-A1 ADAMANTANE DERIVATIVE, RESIN COMPOSITION CONTAINING SAME, AND OPTOELECTRONIC MEMBER AND SEALING AGENT FOR ELECTRONIC CIRCUIT USING THOSE IDEMITSU KOSAN CO., LTD. (JP) 2010-11-25 US disclosed
US-7790917-B2 Adamantyl group-containing epoxy-modified (meth)acrylate and resin composition containing the same IDEMITSU KOSAN CO., LTD. (JP) 2010-09-07 US disclosed
US-7652125-B2 Resin composition, polyimide resin composition, polybenzoxazole resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2010-01-26 US disclosed
US-20090118431-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE COMPANY, LTD (JP) 2009-05-07 US disclosed
US-20090099330-A1 ADAMANTYL GROUP-CONTAINING EPOXY-MODIFIED (METH)ACRYLATE AND RESIN COMPOSITION CONTAINING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-04-16 US disclosed
EP-2014691-A1 ADAMANTYL GROUP-CONTAINING EPOXY-MODIFIED (METH)ACRYLATE AND RESIN COMPOSITION CONTAINING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2009-01-14 EP disclosed
EP-2000510-A1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM Sumitomo Bakelite Company, Ltd. (JP) 2008-12-10 EP disclosed
EP-1985616-A1 ADAMANTANE DERIVATIVE, RESIN COMPOSITION CONTAINING SAME, AND OPTOELECTRONIC MEMBER AND SEALING AGENT FOR ELECTRONIC CIRCUIT USING THOSE Idemitsu Kosan Co., Ltd. (JP) 2008-10-29 EP disclosed
US-20080255335-A1 Resin Composition, Polyimide Resin Composition, Polybenzoxazole Resin Composition, Varnish, Resin Film and Semiconductor Device Using the Same SUMITOMO BAKELITE COMPANY LTD. (JP) 2008-10-16 US disclosed
CN-101031606-A Resin composition, polyimide resin composition, polybenzoxazole resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE CO (JP) 2007-09-05 CN disclosed
EP-1813637-A1 RESIN COMPOSITION, POLYIMIDE RESIN COMPOSITION, POLY- BENZOXAZOLE RESIN COMPOSITION, VARNISHES, RESIN FILMS AND SEMICONDUCTOR DEVICES MADE BY USING THE SAME Sumitomo Bakelite Company, Limited (JP) 2007-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298491-A1 ADAMANTANE DERIVATIVE, RESIN COMPOSITION CONTAINING SAME, AND OPTOELECTRONIC MEMBER AND SEALING AGENT FOR ELECTRONIC CIRCUIT USING THOSE AOC1, ASIC1, ICAM1 MEN1 2523/4885KMT2A 4159/4885POLB 2866/4885
US-20090099330-A1 ADAMANTYL GROUP-CONTAINING EPOXY-MODIFIED (METH)ACRYLATE AND RESIN COMPOSITION CONTAINING THE SAME TAS2R42, MEP1A, TAS2R41 MEN1 1784/4885KMT2A 844/4885POLB 3340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.