SCHEMBL3845870

SCHEMBL3845870

Oc1ccc(C23CC4CC(c5ccc(O)cc5)(C2)CC(C25CC6CC(c7ccc(O)cc7)(CC(c7ccc(O)cc7)(C6)C2)C5)(C4)C3)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.43
ESR2 Q92731 5/20 0.39
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
GFER P55789 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.37
EPHX2 P34913 1/20 0.35
PGR P06401 1/20 0.35
NPC1 O15118 2/20 0.33
RAB9A P51151 1/20 0.33
GRIN2D O15399 2/20 0.33
GRIN3B O60391 2/20 0.33
GRIN1 Q05586 2/20 0.33
GRIN2A Q12879 2/20 0.33
GRIN2B Q13224 2/20 0.33
GRIN2C Q14957 2/20 0.33
GRIN3A Q8TCU5 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3841412 0.96 ESR1 (0.42) ESR1ESR2MEN1POLBGAA
SCHEMBL3841582 0.93 ESR1 (0.46) ESR1MEN1POLBGAAGFER
SCHEMBL6761991 0.92 ESR1 (0.48) ESR1ESR2MEN1POLBGAA
SCHEMBL3844410 0.92 ESR1 (0.51) ESR1MEN1POLBGAAGFER
SCHEMBL20789695 0.83 LMNA (0.50) ESR1ESR2MEN1POLBGAA
SCHEMBL3848262 0.83 ESR1 (0.52) ESR1MEN1POLBGAAGFER
SCHEMBL3843125 0.82 ESR1 (0.52) ESR1MEN1POLBGAAGFER
SCHEMBL17042512 0.81 ESR1 (0.45) ESR1ESR2MEN1POLBGAA
SCHEMBL4054643 0.81 MEN1 (0.47) MEN1POLBGAAGFERKMT2A
SCHEMBL2710962 0.80 GRIN2D (0.50) ALDH1A1LMNAGRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed