SCHEMBL3841582

SCHEMBL3841582

Oc1ccc(C23CC4CC(c5ccc(O)cc5)(C2)CC(C25CC6CC(CC(C6)C2)C5)(C4)C3)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.46
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
GAA P10253 2/20 0.45
POLB P06746 1/20 0.45
GFER P55789 1/20 0.45
ALDH1A1 P00352 4/20 0.44
LMNA P02545 4/20 0.44
EPHX2 P34913 4/20 0.41
NPC1 O15118 2/20 0.40
MAPT P10636 2/20 0.38
XBP1 P17861 1/20 0.38
PGR P06401 1/20 0.38
CNR2 P34972 1/20 0.37
RAB9A P51151 2/20 0.37
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3845870 0.93 ESR1 (0.43) ESR1MEN1KMT2AGAAPOLB
SCHEMBL3844410 0.92 ESR1 (0.51) ESR1MEN1KMT2AGAAPOLB
SCHEMBL3841412 0.90 ESR1 (0.42) ESR1MEN1KMT2AGAAPOLB
SCHEMBL6761991 0.86 ESR1 (0.48) ESR1MEN1KMT2AGAAPOLB
SCHEMBL3848262 0.84 ESR1 (0.52) ESR1MEN1KMT2AGAAPOLB
SCHEMBL3843125 0.83 ESR1 (0.52) ESR1MEN1KMT2AGAAPOLB
SCHEMBL16364512 0.82 ESR1 (0.60) ESR1MEN1KMT2AGAAPOLB
SCHEMBL649556 0.82 ESR1 (0.60) ESR1MEN1KMT2AGAAPOLB
SCHEMBL24559531 0.82 LMNA (0.63) ESR1MEN1KMT2AGAAPOLB
SCHEMBL22644196 0.82 LMNA (0.63) ESR1MEN1KMT2AGAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed