⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27649061 | 0.83 | — | — | |
| SCHEMBL366377 | 0.81 | — | — | |
| SCHEMBL5355267 | 0.81 | — | — | |
| SCHEMBL143769 | 0.79 | FDPS (1.00) | — | |
| SCHEMBL4097085 | 0.78 | FDPS (0.55) | — | |
| Tert-Butylamine SCHEMBL1310969 | 0.77 | FDPS (0.62) | — | |
| Tert-Butylamine SCHEMBL1310967 | 0.77 | FDPS (0.62) | — | |
| SCHEMBL4649888 | 0.77 | — | — | |
| SCHEMBL134918 | 0.77 | — | — | |
| SCHEMBL10946360 | 0.76 | FDPS (0.93) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250319190-A1 | APOE LIPOPROTEIN SYSTEMS | KISBEE THERAPEUTICS INC (US) | 2025-10-16 | — | — | US | disclosed |
| EP-4522646-A2 | APOE LIPOPROTEIN SYSTEMS | Kisbee Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220387-A2 | APOE LIPOPROTEIN SYSTEMS | KISBEE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2014124006-A1 | NANOPARTICLES FOR MAGNETIC RESONANCE IMAGING TRACKING AND METHODS OF MAKING AND USING THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-08-14 | — | — | WO | disclosed |
| US-20090215055-A1 | Genetic Brain Tumor Markers | ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM (NL) | 2009-08-27 | — | — | US | disclosed |
| US-4687666-A | N-PARA-TOSYL-L-LYSINE CHLOROMETHYL KETONE | MINISTERIO DE SANIDAD Y ASISTENCIA SOCIAL INSTITUTO VENEZOLANO DE INVESTIGATIONES CIENTIFICAS (VE) | 1987-08-18 | — | — | US | disclosed |