Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFATC1 | O95644 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3845456 | 0.87 | HDAC2 (0.41) | LMNAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL3850213 | 0.87 | MAPT (0.45) | LMNAMAPTKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3841189 | 0.84 | PTGDR2 (0.42) | NFATC1GSK3BDYRK1AHDAC2HDAC6 | |
| Hydrochloric Acid SCHEMBL3841707 | 0.82 | KDM4E (0.48) | LMNAMAPTKDM4ETP53 | |
| SCHEMBL27917544 | 0.78 | HDAC2 (0.57) | NFATC1GSK3BDYRK1ALMNAMEN1 | |
| SCHEMBL3843455 | 0.78 | ALDH1A1 (0.49) | LMNAMAPTKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3843975 | 0.77 | CYP11B1 (0.45) | MAPTMEN1KMT2ATP53POLB | |
| Hydrochloric Acid SCHEMBL3842265 | 0.75 | KDM5A (0.49) | NFATC1GSK3BDYRK1AKDM4E | |
| SCHEMBL1737728 | 0.73 | MCL1 (0.42) | LMNAMAPTKDM4ECYP17A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL3852857 | 0.73 | ROCK2 (0.48) | LMNAMAPTKDM4ECYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-A4 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2009-09-09 | — | — | EP | claimed |
| JP-2008511621-A | — | — | 2008-04-17 | — | — | JP | claimed |
| EP-1784404-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | claimed |
| WO-2006025716-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |