SCHEMBL3846356

SCHEMBL3846356

C(#CC12CC3CC(C1)CC(C1C4CC5CC(C4)CC1(C#Cc1ccccc1)C5)(C3)C2)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.32
FPR1 P21462 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4104795 0.79 APP (0.39) GRM5
SCHEMBL2747858 0.76 APP (0.42) GRM5FPR1
SCHEMBL3845906 0.75 APP (0.35) GRM5FPR1
SCHEMBL2188668 0.75 GRM5 (0.37) GRM5
SCHEMBL2192814 0.72 GRM5 (0.35) GRM5
SCHEMBL4104803 0.72 GRIN2D (0.54) GRM5
SCHEMBL2188183 0.70 GRM5 (0.35) GRM5
SCHEMBL4100078 0.70 APP (0.42) GRM5
SCHEMBL2186702 0.69 APP (0.32) GRM5
SCHEMBL3843841 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed