Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FPR1 | P21462 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2747858 | 0.77 | APP (0.42) | APPHSD11B1GRM5FAAHMEN1 | |
| SCHEMBL3846356 | 0.75 | GRM5 (0.32) | GRM5FPR1 | |
| SCHEMBL3845676 | 0.72 | APP (0.35) | APPHSD11B1GRM5FFAR1KCNH2 | |
| SCHEMBL4104795 | 0.70 | APP (0.39) | APPHSD11B1GRM5FAAHKMT2A | |
| SCHEMBL15774268 | 0.70 | GRM5 (0.36) | APPHSD11B1GRM5MEN1KMT2A | |
| SCHEMBL3849558 | 0.69 | GRIN2D (0.30) | — | |
| SCHEMBL6765059 | 0.68 | HSD11B1 (0.36) | APPHSD11B1GRM5FAAHMEN1 | |
| SCHEMBL6684731 | 0.67 | LMNA (0.53) | APPHSD11B1MEN1KMT2AFFAR1 | |
| SCHEMBL2186702 | 0.67 | APP (0.32) | APPGRM5 | |
| SCHEMBL6683935 | 0.67 | GRIN2D (0.33) | APPFPR1P2RX7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318610-A1 | ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES | SUMITOMO BAKELITE CO., LTD (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2117009-A1 | ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE | Sumitomo Bakelite Co., Ltd. (JP) | 2009-11-11 | — | — | EP | disclosed |