SCHEMBL3846362

SCHEMBL3846362

CC(C)c1c(C(=O)O)c(C(=O)O)c2ccccc2c1C(C)C

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ LDHA P00338 6/20 0.46
▸ LDHB P07195 5/20 0.46
▸ ALB P02768 3/20 0.46
▸ KDM4E B2RXH2 3/20 0.42
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ GLA P06280 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.41
▸ PDE10A Q9Y233 3/20 0.40
▸ DHODH Q02127 2/20 0.40
▸ EGFR P00533 1/20 0.38
▸ FABP3 P05413 1/20 0.37
▸ FABP4 P15090 1/20 0.37
▸ TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27745289 0.92 LDHA (0.46) LDHALDHBALBKDM4EMEN1
SCHEMBL26027710 0.83 LDHA (0.66) LDHALDHBALBKDM4EMEN1
SCHEMBL54422 0.76 KDM4E (0.58) LDHAKDM4EMEN1KMT2AALDH1A1
SCHEMBL29504076 0.74 LDHA (0.44) LDHALDHBALBCYP1A2FABP3
SCHEMBL28383554 0.74 KDM4E (0.56) LDHAKDM4EMEN1KMT2AALDH1A1
SCHEMBL16616351 0.74 KDM4E (0.56) LDHAKDM4EMEN1KMT2AALDH1A1
SCHEMBL31441237 0.74 KDM4E (0.56) LDHAKDM4EMEN1KMT2AALDH1A1
SCHEMBL5441713 0.74 LDHA (0.44) LDHALDHBALBCYP1A2FABP3
SCHEMBL31386574 0.74 KDM4E (0.56) LDHAKDM4EMEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL16014117 0.74 KDM4E (0.56) LDHAKDM4EMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1197799-B1 Silver halide photographic light-sensitive material comprising a yellow dye-forming coupler, and method for producing a yellow azomethine dye FUJIFILM CORP (JP) 2009-11-11 — — EP disclosed
US-7196194-B2 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD (JP) 2007-03-27 — — US disclosed
EP-1193548-B1 Silver halide color photographic light-sensitive material, pyrrolotriazole compound, and dye-forming compound FUJI PHOTO FILM CO LTD (JP) 2006-06-21 — — EP disclosed
US-7009048-B2 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye FUJI PHOTO FILM CO., LTD. (JP) 2006-03-07 — — US disclosed
EP-1139170-B1 Silver halide color photographic light-sensitive material, pyrrolotriazole compound and dye-forming compound FUJI PHOTO FILM CO LTD (JP) 2006-01-25 — — EP disclosed
US-20050020821-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye FUJI PHOTO FILM CO., LTD. 2005-01-27 — — US disclosed
US-6803181-B2 USING A 1,3-DIKETOOXAZOLIDINE FUJI PHOTO FILM CO., LTD. (JP) 2004-10-12 — — US disclosed
US-6773875-B2 CYAN COUPLER CONTAINING PYRROLOTRIAZOLE COMPOUND SUBSTITUTED WITH NITRILE, ESTER, CARBAMIDE AND SUBSTITUTED OR NONSUBSTITUTED BENZENE RING FUJI PHOTO FILM CO., LTD. (JP) 2004-08-10 — — US disclosed
US-20040122238-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD. 2004-06-24 — — US disclosed
US-20040096787-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD. 2004-05-20 — — US disclosed
US-6649771-B2 Color reproduction FUJI PHOTO FILM CO., LTD. (JP) 2003-11-18 — — US disclosed
US-20030073047-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJIFILM CORPORATION (JP) 2003-04-17 — — US disclosed
EP-1246006-A2 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD. (JP) 2002-10-02 — — EP disclosed
US-20020076664-A1 Silver halide color photographic light-sensitive material, pyrrolotriazole compound, and dye-forming compound FUJI PHOTO FILM CO., LTD. 2002-06-20 — — US disclosed
US-20020064736-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye FUJI PHOTO FILM CO., LTD. 2002-05-30 — — US disclosed
EP-1197799-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye Fuji Photo Film Co., Ltd. (JP) 2002-04-17 — — EP disclosed
EP-1193548-A2 Silver halide color photographic light-sensitive material, pyrrolotriazole compound, and dye-forming compound Fuji Photo Film Co., Ltd. (JP) 2002-04-03 — — EP disclosed
US-20020031736-A1 Silver halide color photographic light-sensitive material, pyrrolotriazole compound and dye-forming compound FUJIFILM CORPORATION (JP) 2002-03-14 — — US disclosed
EP-1139170-A2 Silver halide color photographic light-sensitive material, pyrrolotriazole compound and dye-forming compound Fuji Photo Film Co., Ltd. (JP) 2001-10-04 — — EP disclosed
US-5024924-A Reduced replenishment rate of developing bath, stability of photographic properties FUJI PHOTO FILM CO., LTD. (JP) 1991-06-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020064736-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye CBR1, IK, CBR3 LDHA 867/4885LDHB 918/4885ALB 2235/4885
US-20030073047-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound CBR1, IK, CBR3 LDHA 593/4885LDHB 647/4885ALB 3503/4885
US-20020076664-A1 Silver halide color photographic light-sensitive material, pyrrolotriazole compound, and dye-forming compound CBR3, IK, CBR1 LDHA 2196/4885LDHB 2095/4885ALB 2929/4885
US-20040122238-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound CBR1, CBR3, IK LDHA 871/4885LDHB 836/4885ALB 3843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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