SCHEMBL26027710

SCHEMBL26027710

CC(C)c1c(O)c(O)c(C(=O)O)c2ccccc12

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ LDHA P00338 12/20 0.66
▸ LDHB P07195 11/20 0.66
▸ ALB P02768 3/20 0.66
▸ DHODH Q02127 3/20 0.44
▸ PDE10A Q9Y233 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ GLA P06280 1/20 0.41
▸ HPGD P15428 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29260803 0.84 DHODH (0.55) LDHALDHBALBDHODHPDE10A
SCHEMBL27745289 0.83 LDHA (0.46) LDHALDHBALBDHODHPDE10A
SCHEMBL3846362 0.83 LDHA (0.46) LDHALDHBALBDHODHPDE10A
SCHEMBL29750641 0.80 LDHA (1.00) LDHALDHBALBDHODH
SCHEMBL426471 0.80 LDHA (1.00) LDHALDHBALBDHODH
SCHEMBL19202239 0.78 LDHA (0.43) LDHALDHBALBKDM4EMEN1
SCHEMBL6450325 0.78 DHODH (0.50) LDHALDHBALBDHODHPDE10A
SCHEMBL31039922 0.78 DHODH (0.50) LDHALDHBALBDHODHPDE10A
SCHEMBL19203138 0.77 LDHA (0.66) LDHALDHBALBDHODHPDE10A
SCHEMBL7173943 0.76 LDHA (1.00) LDHALDHBALBKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11739223-B2 Surface primer compositions and methods of use ENVISTA (US) 2023-08-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739223-B2 Surface primer compositions and methods of use SP1, GPER1, GRIN1 LDHA 2656/4885LDHB 2298/4885ALB 1999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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