SCHEMBL3846367

SCHEMBL3846367

CC(C)c1cc2ccccc2c(C(=O)O)c1C(C)C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
KDM4E B2RXH2 1/20 0.58
ALDH1A1 P00352 1/20 0.58
CYP1A2 P05177 1/20 0.58
GLA P06280 1/20 0.58
HPGD P15428 1/20 0.58
CYP2C19 P33261 1/20 0.58
HSD17B10 Q99714 1/20 0.58
FABP3 P05413 2/20 0.43
FABP4 P15090 2/20 0.43
LDHA P00338 4/20 0.41
LDHB P07195 3/20 0.41
ALB P02768 3/20 0.41
ME2 P23368 1/20 0.40
ME1 P48163 1/20 0.40
ME3 Q16798 1/20 0.40
AKR1B1 P15121 1/20 0.39
PDE10A Q9Y233 2/20 0.39
DHODH Q02127 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17323561 0.89 MEN1 (0.55) MEN1KMT2AKDM4EALDH1A1CYP1A2
SCHEMBL9847917 0.87 MEN1 (0.61) MEN1KMT2AKDM4EALDH1A1CYP1A2
SCHEMBL21686487 0.84 CYP1A2 (0.58) MEN1KMT2AKDM4EALDH1A1CYP1A2
SCHEMBL19203291 0.81 CYP1A2 (0.53) MEN1KMT2AKDM4EALDH1A1CYP1A2
SCHEMBL28152064 0.79 F2 (0.39) MEN1KMT2AKDM4EALDH1A1CYP1A2
SCHEMBL248045 0.78 KDM4E (0.53) MEN1KMT2AKDM4EALDH1A1CYP1A2
SCHEMBL28748356 0.77 NCEH1 (0.41) MEN1KMT2AKDM4EALDH1A1CYP1A2
SCHEMBL3846363 0.77 HSD17B10 (0.44) MEN1KMT2AKDM4EALDH1A1CYP1A2
SCHEMBL72911 0.77 SIGMAR1 (0.39) ALDH1A1CYP1A2CYP2C19HSD17B10NCEH1
SCHEMBL6909795 0.76 GABRA1 (0.42) CYP1A2HPGDCYP2C19GABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1197799-B1 Silver halide photographic light-sensitive material comprising a yellow dye-forming coupler, and method for producing a yellow azomethine dye FUJIFILM CORP (JP) 2009-11-11 EP disclosed
US-7196194-B2 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD (JP) 2007-03-27 US disclosed
EP-1193548-B1 Silver halide color photographic light-sensitive material, pyrrolotriazole compound, and dye-forming compound FUJI PHOTO FILM CO LTD (JP) 2006-06-21 EP disclosed
CN-1761632-A Sacrificial agents for fly ash concrete HANDY CHEMICALS LTD (CA) 2006-04-19 CN disclosed
US-7009048-B2 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye FUJI PHOTO FILM CO., LTD. (JP) 2006-03-07 US disclosed
EP-1139170-B1 Silver halide color photographic light-sensitive material, pyrrolotriazole compound and dye-forming compound FUJI PHOTO FILM CO LTD (JP) 2006-01-25 EP disclosed
US-20050020821-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye FUJI PHOTO FILM CO., LTD. 2005-01-27 US disclosed
US-6803181-B2 USING A 1,3-DIKETOOXAZOLIDINE FUJI PHOTO FILM CO., LTD. (JP) 2004-10-12 US disclosed
US-6773875-B2 CYAN COUPLER CONTAINING PYRROLOTRIAZOLE COMPOUND SUBSTITUTED WITH NITRILE, ESTER, CARBAMIDE AND SUBSTITUTED OR NONSUBSTITUTED BENZENE RING FUJI PHOTO FILM CO., LTD. (JP) 2004-08-10 US disclosed
US-20040122238-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD. 2004-06-24 US disclosed
US-6649771-B2 Color reproduction FUJI PHOTO FILM CO., LTD. (JP) 2003-11-18 US disclosed
US-20030073047-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJIFILM CORPORATION (JP) 2003-04-17 US disclosed
EP-1246006-A2 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD. (JP) 2002-10-02 EP disclosed
US-20020076664-A1 Silver halide color photographic light-sensitive material, pyrrolotriazole compound, and dye-forming compound FUJI PHOTO FILM CO., LTD. 2002-06-20 US disclosed
US-20020064736-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye FUJI PHOTO FILM CO., LTD. 2002-05-30 US disclosed
EP-1197799-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye Fuji Photo Film Co., Ltd. (JP) 2002-04-17 EP disclosed
EP-1193548-A2 Silver halide color photographic light-sensitive material, pyrrolotriazole compound, and dye-forming compound Fuji Photo Film Co., Ltd. (JP) 2002-04-03 EP disclosed
US-20020031736-A1 Silver halide color photographic light-sensitive material, pyrrolotriazole compound and dye-forming compound FUJIFILM CORPORATION (JP) 2002-03-14 US disclosed
EP-1139170-A2 Silver halide color photographic light-sensitive material, pyrrolotriazole compound and dye-forming compound Fuji Photo Film Co., Ltd. (JP) 2001-10-04 EP disclosed
US-5024924-A Reduced replenishment rate of developing bath, stability of photographic properties FUJI PHOTO FILM CO., LTD. (JP) 1991-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020064736-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye CBR1, IK, CBR3 MEN1 951/4885KMT2A 1150/4885KDM4E 1803/4885
US-20030073047-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound CBR1, IK, CBR3 MEN1 195/4885KMT2A 870/4885KDM4E 2484/4885
US-20020076664-A1 Silver halide color photographic light-sensitive material, pyrrolotriazole compound, and dye-forming compound CBR3, IK, CBR1 MEN1 2372/4885KMT2A 1440/4885KDM4E 2996/4885
US-20040122238-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound CBR1, CBR3, IK MEN1 110/4885KMT2A 1061/4885KDM4E 2508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.