Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15068102 | 0.80 | GAA (0.43) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL28403962 | 0.80 | HPGD (0.42) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6600620 | 0.80 | ALDH1A1 (0.33) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL15066522 | 0.80 | MAPT (0.38) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL15066907 | 0.80 | MAPT (0.41) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL920851 | 0.80 | MAPT (0.41) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9230402 | 0.80 | ALDH1A1 (0.42) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL3841411 | 0.79 | ALDH1A1 (0.35) | ALDH1A1KDM4E | |
| SCHEMBL3845340 | 0.79 | AOC3 (0.30) | — | |
| SCHEMBL3845339 | 0.79 | AOC3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041388-B1 | Substituted poly(arylene vinylenes), process for their preparation and their use in electroluminescent devices | SEMICONDUCTORS GMBH (DE) | 2006-05-09 | — | — | US | claimed |
| EP-1043988-A4 | C-10 CARBON-SUBSTITUTED ARTEMISININ-LIKE TRIOXANE COMPOUNDS HAVING ANTIMALARIAL, ANTIPROLIFERATIVE AND ANTITUMOUR ACTIVITIES | HAUSER INC (US) | 2001-10-31 | — | — | EP | claimed |
| EP-1043988-A1 | C-10 CARBON-SUBSTITUTED ARTEMISININ-LIKE TRIOXANE COMPOUNDS HAVING ANTIMALARIAL, ANTIPROLIFERATIVE AND ANTITUMOUR ACTIVITIES | Hauser Inc. (US) | 2000-10-18 | — | — | EP | claimed |
| WO-1999033461-A1 | C-10 CARBON-SUBSTITUTED ARTEMISININ-LIKE TRIOXANE COMPOUNDS HAVING ANTIMALARIAL, ANTIPROLIFERATIVE AND ANTITUMOUR ACTIVITIES | HAUSER, INC. (US) | 1999-07-08 | — | — | WO | claimed |
| US-20090318610-A1 | ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES | SUMITOMO BAKELITE CO., LTD (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2117009-A1 | ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE | Sumitomo Bakelite Co., Ltd. (JP) | 2009-11-11 | — | — | EP | disclosed |