SCHEMBL9230402

SCHEMBL9230402

C=CCOc1cc[c]c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
GAA P10253 2/20 0.42
HPGD P15428 2/20 0.42
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ADRA2A P08913 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
MAOA P21397 1/20 0.40
CA12 O43570 5/20 0.40
CA1 P00915 5/20 0.40
CA9 Q16790 5/20 0.40
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3846804 0.80 MAPT (0.42) ALDH1A1GAAHPGDMAPTMEN1
SCHEMBL15066907 0.79 MAPT (0.41) ALDH1A1GAAHPGDMAPTMEN1
SCHEMBL920851 0.79 MAPT (0.41) ALDH1A1GAAHPGDMAPTMEN1
SCHEMBL160560 0.77 NQO1 (0.46) ALDH1A1HPGDMAPTMEN1LMNA
SCHEMBL27982310 0.76 MAPT (0.40) ALDH1A1GAAHPGDMAPTMEN1
SCHEMBL9834426 0.75 LMNA (0.39) ALDH1A1GAAHPGDMAPTMEN1
SCHEMBL28253174 0.75 MAPT (0.39) ALDH1A1GAAHPGDMAPTMEN1
SCHEMBL9738774 0.75 MAPT (0.42) ALDH1A1GAAHPGDMAPTMEN1
SCHEMBL160643 0.74 KMT2A (0.41) MAPTMEN1KMT2AMAOACA12
SCHEMBL17397326 0.73 MAOA (0.38) ALDH1A1HPGDMAOACYP2D6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115397891-B Polysiloxanes with radiation-crosslinkable and moisture-crosslinkable groups 瓦克化学股份公司 2024-02-02 CN disclosed
US-20230167246-A1 Polysiloxanes with radiation- and moisture-cross-linkable groups WACKER CHEMIE AG (DE) 2023-06-01 US disclosed
EP-4136137-A1 POLYSILOXANES WITH RADIATION- AND MOISTURE-CROSS-LINKABLE GROUPS Wacker Chemie AG (DE) 2023-02-22 EP disclosed
CN-115397891-A Polysiloxanes with radiation-crosslinkable and moisture-crosslinkable groups 瓦克化学股份公司 2022-11-25 CN disclosed
CN-107266382-B Heteroarylpiperidine and piperazine derivatives as fungicides 拜耳知识产权有限责任公司 2020-10-27 CN disclosed
US-10426169-B2 Heteroarylpiperidine and -piperazine derivatives as fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2019-10-01 US disclosed
EP-2921485-B1 ISOXAZOLE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2018-07-18 EP disclosed
EP-2921484-B1 OXAZOLE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2018-07-18 EP disclosed
US-20180103641-A1 HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-04-19 US disclosed
EP-2921495-B1 HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES BAYER IP GMBH (DE) 2018-03-28 EP disclosed
EP-2921491-A1 INTERMEDIATES FOR THE PRODUCTION OF HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES Bayer Intellectual Property GmbH (DE) 2015-09-23 EP disclosed
EP-2921484-A1 OXAZOLE DERIVATIVES Bayer Intellectual Property GmbH (DE) 2015-09-23 EP disclosed
EP-2921494-A1 HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES Bayer Intellectual Property GmbH (DE) 2015-09-23 EP disclosed
EP-2921493-A1 HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES Bayer Intellectual Property GmbH (DE) 2015-09-23 EP disclosed
EP-2921481-A1 4-PIPERIDINE CARBOXYLIC ACID DERIVATIVES Bayer Intellectual Property GmbH (DE) 2015-09-23 EP disclosed
EP-2921495-A1 HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES Bayer Intellectual Property GmbH (DE) 2015-09-23 EP disclosed
US-20150024935-A1 HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-01-22 US disclosed
EP-2797899-A2 HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES Bayer Intellectual Property GmbH (DE) 2014-11-05 EP disclosed
WO-2013098229-A2 HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-07-04 WO disclosed
US-5420222-A Curable organo(poly)siloxane compositions WACKER-CHEMIE GMBH (DE) 1995-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10426169-B2 Heteroarylpiperidine and -piperazine derivatives as fungicides RB1, RBX1, RRP12 ALDH1A1 1534/4885GAA 1717/4885HPGD 3001/4885
US-20180103641-A1 HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES RB1, RBX1, RRP12 ALDH1A1 1534/4885GAA 1717/4885HPGD 3001/4885
US-20150024935-A1 HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES RB1, RBX1, RRP12 ALDH1A1 1608/4885GAA 1939/4885HPGD 3059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.