Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1735789 | 0.99 | KDM4E (0.42) | KDM4EHSD17B10MEN1KMT2APDE10A | |
| SCHEMBL1735360 | 0.91 | WNT3A (0.38) | KDM4EHSD17B10MEN1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL1736693 | 0.90 | WNT3A (0.38) | KDM4EHSD17B10MEN1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL1736667 | 0.88 | CYP1A2 (0.39) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL1736593 | 0.88 | LRRK2 (0.42) | KDM4EHSD17B10PDE10AALDH1A1HPGD | |
| SCHEMBL3843126 | 0.84 | MEN1 (0.45) | KDM4EHSD17B10MEN1KMT2APDE4B | |
| Hydrochloric Acid SCHEMBL1738613 | 0.83 | FABP4 (0.47) | KDM4EMEN1KMT2AUTS2RNOS2 | |
| Hydrochloric Acid SCHEMBL1737814 | 0.83 | KMT2A (0.44) | KDM4EHSD17B10MEN1KMT2APDE4B | |
| SCHEMBL2480169 | 0.82 | CYP3A4 (0.47) | KDM4EMEN1KMT2APDE4BUTS2R | |
| Hydrochloric Acid SCHEMBL1735367 | 0.81 | KMT2A (0.43) | KDM4EHSD17B10MEN1KMT2AUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-A4 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2009-09-09 | — | — | EP | disclosed |
| EP-1784404-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006025716-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |