Fluorescein

Fluorescein

SCHEMBL384697

CC(=O)C(C)=O.O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccccc21

nearest known ligand 0.87

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FTO Q9C0B1 8/20 0.87
▸ MAPT P10636 5/20 0.87
▸ MEN1 O00255 5/20 0.87
▸ KMT2A Q03164 5/20 0.87
▸ TDP1 Q9NUW8 4/20 0.87
▸ HTT P42858 2/20 0.87
▸ HPGD P15428 2/20 0.87
▸ RECQL P46063 2/20 0.87
▸ BLM P54132 2/20 0.87
▸ PRMT1 Q99873 2/20 0.87
▸ ACE2 Q9BYF1 2/20 0.87
▸ CYP2C19 P33261 1/20 0.87
▸ SMAD3 P84022 1/20 0.87
▸ LMNA P02545 4/20 0.66
▸ ALDH1A1 P00352 3/20 0.66
▸ USP2 O75604 2/20 0.66
▸ GPR55 Q9Y2T6 2/20 0.65
▸ ALOX12 P18054 2/20 0.65
▸ POLB P06746 2/20 0.65
▸ NPSR1 Q6W5P4 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorescein SCHEMBL28442968 0.96 FTO (0.89) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL4235133 0.95 FTO (0.87) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL20239317 0.95 FTO (0.87) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL2361033 0.95 FTO (0.87) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL27647697 0.94 FTO (0.85) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL6231484 0.94 FTO (0.85) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL3892589 0.94 FTO (0.85) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL8648355 0.93 FTO (0.94) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL30272223 0.93 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL29371199 0.93 FTO (1.00) FTOMAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 383 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117665177-A Method for detecting sodium fluorescein related substances 广西梧州制药(集团)股份有限公司 2024-03-08 — — CN claimed
CN-117285500-A Preparation method of high-purity sodium fluorescein 广西梧州制药(集团)股份有限公司 2023-12-26 — — CN claimed
CN-113461651-A Purification method of high-purity fluorescein 山东绅联药业有限公司 2021-10-01 — — CN claimed
US-11085065-B2 Phenotypic engineering of spores Rotman, M. Boris (US) 2021-08-10 — — US claimed
CN-110004056-B Cell quantity and cell activity detection method and detection cavity device for tissue engineering reactor 北京航空航天大学 2020-12-11 — — CN claimed
CN-109609583-A Embryo's colouring method, the method and kit for judging Embryo viability 北京农学院 2019-04-12 — — CN claimed
US-20170292143-A1 Phenotypic engineering of spores SUSSMAN, Daniel J. 2017-10-12 — — US claimed
CN-101535496-B Genetically engineered biological indicator AMERICAN STERILIZER CO. (US) 2015-12-02 — — CN claimed
CN-101541944-B Sterilization indicator AMERICAN STERILIZER CO 2013-05-22 — — CN claimed
CN-101605796-A Basically pure fluorescein ALCON MFG LTD (US) 2009-12-16 — — CN claimed
CN-101541944-A Sterilization indicator AMERICAN STERILIZER CO (US) 2009-09-23 — — CN claimed
CN-101535496-A Genetically engineered biological indicator AMERICAN STERILIZER CO (US) 2009-09-16 — — CN claimed
US-20030060441-A1 Nucleic acid triggered catalytic drug and probe release TAYLOR JOHN-STEPHEN (US) 2003-03-27 — — US claimed
CN-117225007-B Method for removing residual solvent in sodium fluorescein 珠海前列药业有限公司 2026-05-22 — — CN disclosed
CN-118159262-A Three-dose therapy for cancer treatment 细胞疗法公司 2024-06-07 — — CN disclosed
CN-117665177-A Method for detecting sodium fluorescein related substances 广西梧州制药(集团)股份有限公司 2024-03-08 — — CN disclosed
EP-0745132-A1 METHOD FOR PREPARING ORPHAN RECEPTOR LIGANDS ZymoGenetics, Inc. (US) 1996-12-04 — — EP disclosed
US-5541085-A Method for preparing orphan receptor ligands ZYMOGENETICS, INC. (US) 1996-07-30 — — US disclosed
WO-1995021930-A2 METHOD FOR PREPARING ORPHAN RECEPTOR LIGANDS ZYMOGENETICS, INC. (US) 1995-08-17 — — WO disclosed
WO-1994024166-A1 UNIQUE SPERM ANTIGENS AND METHODS OF USE MEDICAL UNIVERSITY OF SOUTH CAROLINA (US) 1994-10-27 — — WO disclosed
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