Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29275459 | 0.82 | MAPT (0.61) | MAPTHPGDGAARAB9AKDM1A | |
| SCHEMBL7385247 | 0.80 | MAPT (0.57) | MAPTKMT2ACYP3A4KCNH2 | |
| SCHEMBL4110940 | 0.78 | MAPT (0.86) | MAPTHPGDGAARAB9AKMT2A | |
| SCHEMBL28049259 | 0.75 | MAPT (0.65) | MAPTHPGDGAARAB9AKMT2A | |
| SCHEMBL20734732 | 0.75 | MAPT (0.65) | MAPTHPGDGAARAB9AKMT2A | |
| SCHEMBL20734734 | 0.75 | MAPT (0.65) | MAPTHPGDGAARAB9AKMT2A | |
| SCHEMBL2030597 | 0.74 | MAPT (0.59) | MAPTKMT2ACYP3A4KCNH2 | |
| SCHEMBL1024478 | 0.74 | MAPT (0.59) | MAPTKMT2ACYP3A4KCNH2 | |
| SCHEMBL27815326 | 0.74 | MAPT (0.59) | MAPTKMT2ACYP3A4KCNH2 | |
| SCHEMBL15397577 | 0.74 | MAPT (0.59) | MAPTKMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099815-A2 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | Acure Pharma AB (SE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008058679-A2 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ACURE PHARMA AB (SE) | 2008-05-22 | — | — | WO | disclosed |