Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.49 |
| ▸ | KLK1 | P06870 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489461 | 0.98 | GAA (0.55) | GAALMNASRD5A2ELANECA2 | |
| SCHEMBL29833587 | 0.93 | LMNA (0.69) | GAALMNASRD5A2ELANECA2 | |
| 4-(Acetate)Acetophenone SCHEMBL30735795 | 0.91 | SRD5A2 (0.55) | GAALMNASRD5A2ELANEHSD17B10 | |
| SCHEMBL29674918 | 0.91 | KMT2A (0.55) | GAALMNASRD5A2ELANECA2 | |
| SCHEMBL7735335 | 0.90 | FFAR1 (0.54) | GAALMNASRD5A2HSD17B10ALDH1A1 | |
| Acetic Acid Phenyl Ester SCHEMBL29375775 | 0.89 | AKR1B1 (0.63) | GAALMNASRD5A2ELANEPTGS1 | |
| SCHEMBL23751423 | 0.88 | SRD5A2 (0.58) | GAALMNASRD5A2CA2CAMK2A | |
| Phenylacetic Acid SCHEMBL27672920 | 0.86 | LMNA (0.65) | GAALMNASRD5A2ELANEPOLB | |
| 4-Nitrophenyl Acetate SCHEMBL29433136 | 0.86 | BCL9 (0.52) | GAASRD5A2ALDH1A1 | |
| SCHEMBL8037879 | 0.86 | POLB (0.61) | GAALMNAELANEHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215879-B | 3-aryl-4, 5-pyranocoumarin derivative, and preparation method and application thereof | 广西中医药大学 | 2023-10-20 | — | — | CN | claimed |
| CN-115215879-A | 3-aryl-4, 5-pyranocoumarin derivatives, and preparation method and application thereof | 广西中医药大学 | 2022-10-21 | — | — | CN | claimed |
| EP-0238061-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS | Banyu Pharmaceutical Co., Ltd. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4880797-A | THIAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-11-14 | — | — | US | claimed |
| EP-0238061-A2 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1987-09-23 | — | — | EP | claimed |
| CN-115215879-B | 3-aryl-4, 5-pyranocoumarin derivative, and preparation method and application thereof | 广西中医药大学 | 2023-10-20 | — | — | CN | disclosed |
| CN-115215879-A | 3-aryl-4, 5-pyranocoumarin derivatives, and preparation method and application thereof | 广西中医药大学 | 2022-10-21 | — | — | CN | disclosed |
| US-9751830-B2 | Inhibitors of the tumor necrosis factor receptor complex | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-09-05 | — | — | US | disclosed |
| US-9481670-B2 | Triazine compounds | SPHAERA PHARMA PTE. LTD. (SG) | 2016-11-01 | — | — | US | disclosed |
| US-9265739-B2 | Methods and use of compounds that bind to HER2/neu receptor complex | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-02-23 | — | — | US | disclosed |
| US-20150368187-A1 | INHIBITORS OF THE TUMOR NECROSIS FACTOR RECEPTOR COMPLEX | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2015-12-24 | — | — | US | disclosed |
| US-9012603-B2 | Peptides that block the binding of IgG to FcRn | BIOGEN IDEC HEMOPHILIA INC. (US) | 2015-04-21 | — | — | US | disclosed |
| EP-0089710-B1 | NOVEL HYDROXYPHENYLACETAMIDES HAVING ANALGESIC AND ANTI-IRRITANT ACTIVITY | THE PROCTER & GAMBLE COMPANY (US) | 1985-07-31 | — | — | EP | disclosed |
| EP-0066993-B1 | QUINOLINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-01-30 | — | — | EP | disclosed |
| US-4435405-A | 2-(AMINOALKYLTHIO) SUBSTITUTED | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-03-06 | — | — | US | disclosed |
| US-4424205-A | DEPILLATORIES | THE PROCTER & GAMBLE COMPANY (US) | 1984-01-03 | — | — | US | disclosed |
| EP-0089710-A1 | Novel hydroxyphenylacetamides having analgesic and anti-irritant activity | THE PROCTER & GAMBLE COMPANY (US) | 1983-09-28 | — | — | EP | disclosed |
| EP-0066993-A1 | Quinoline derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-15 | — | — | EP | disclosed |
| US-4233217-A | USED AS ANALGESICS, NARCOTIC ANTAGONISTS, AND ANTIHISTAMINES | PENNWALT CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |
| US-4210749-A | USED AS ANALGESICS, NARCOTIC ANTAGONISTS | PENNWALT CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368187-A1 | INHIBITORS OF THE TUMOR NECROSIS FACTOR RECEPTOR COMPLEX | TNFRSF1A, TNF, TNFRSF9 | GAA 1178/4885LMNA 2928/4885SRD5A2 1373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.