Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384743 | 0.86 | GAA (0.57) | POLBLMNAGAAMAPTPKM | |
| SCHEMBL11489461 | 0.84 | GAA (0.55) | POLBLMNAGAAMAPTPKM | |
| SCHEMBL10568442 | 0.84 | LMNA (0.59) | POLBLMNAGAAMAPTPKM | |
| SCHEMBL11531056 | 0.84 | LMNA (0.53) | POLBLMNAGAAMAPTPKM | |
| SCHEMBL1849340 | 0.84 | LMNA (0.53) | POLBLMNAGAAMAPTPKM | |
| SCHEMBL18219806 | 0.84 | HTT (0.47) | POLBLMNAGAAMAPTPKM | |
| SCHEMBL13666968 | 0.84 | TSHR (0.47) | POLBLMNAGAAMAPTPKM | |
| SCHEMBL10774498 | 0.83 | POLB (0.66) | POLBLMNAGAAMAPTALDH1A1 | |
| SCHEMBL777803 | 0.83 | ELANE (0.62) | POLBLMNAGAAMAPTPKM | |
| SCHEMBL9081470 | 0.83 | LMNA (0.61) | POLBLMNAGAAMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548774-B1 | Process for producing a lactone or an ester | SUMITOMO CHEMICAL CO (JP) | 2000-03-15 | — | — | EP | disclosed |
| EP-0914318-A1 | PYRAZINES | KINGS COLLEGE LONDON (GB) | 1999-05-12 | — | — | EP | disclosed |
| WO-1997043267-A1 | PYRAZINES | KINGS COLLEGE LONDON (GB) | 1997-11-20 | — | — | WO | disclosed |
| US-5405974-A | Reacting a ketone, oxygen, an aromatic aldehyde using an aromatic solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0548774-A1 | Process for producing a lactone or an ester | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-4530842-A | Containing a cyano substitution in position 3 | SANDOZ LTD. (CH) | 1985-07-23 | — | — | US | disclosed |