Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388229 | 0.86 | — | — | |
| SCHEMBL28493311 | 0.82 | TSHR (0.38) | TSHRHPGDALDH1A1ADRB2ADRB1 | |
| SCHEMBL389423 | 0.82 | TSHR (0.38) | TSHRHPGDALDH1A1ADRB2ADRB1 | |
| SCHEMBL28500505 | 0.80 | TSHR (0.36) | TSHRHPGDALDH1A1ADRB2ADRB1 | |
| SCHEMBL1228489 | 0.76 | TSHR (0.40) | TSHRHPGDALDH1A1ADRB2ADRB1 | |
| SCHEMBL4221286 | 0.76 | TSHR (0.40) | TSHRHPGDALDH1A1ADRB2ADRB1 | |
| SCHEMBL129087 | 0.76 | TSHR (0.40) | TSHRHPGDALDH1A1ADRB2ADRB1 | |
| SCHEMBL388224 | 0.75 | — | — | |
| SCHEMBL15302455 | 0.74 | TSHR (0.39) | TSHRHPGDALDH1A1ADRB2ADRB1 | |
| SCHEMBL537953 | 0.74 | TSHR (0.39) | TSHRHPGDALDH1A1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101697-B2 | Multi-functionalized high-trans elastomeric polymers | BRIDGESTONE CORPORATION (JP) | 2012-01-24 | — | — | US | claimed |
| US-20060173145-A1 | Multi-functionalized high-trans elastomeric polymers | BRIDGESTONE CORPORATION (JP) | 2006-08-03 | — | — | US | claimed |
| CN-112126065-B | Preparation method of solid silicon carbide ceramic precursor | 宁波曙翔新材料股份有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-112279665-B | Wave-absorbing ceramic precursor and preparation method and application thereof | 浙江华茂航天科技股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-112094414-B | Preparation method of novel liquid silicon carbide ceramic precursor | 宁波曙翔新材料股份有限公司 | 2022-01-07 | — | — | CN | disclosed |
| CN-112094414-A | Preparation method of novel liquid silicon carbide ceramic precursor | 宁波曙翔新材料股份有限公司 | 2020-12-18 | — | — | CN | disclosed |
| US-8101697-B2 | Multi-functionalized high-trans elastomeric polymers | BRIDGESTONE CORPORATION (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20060173145-A1 | Multi-functionalized high-trans elastomeric polymers | BRIDGESTONE CORPORATION (JP) | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173145-A1 | Multi-functionalized high-trans elastomeric polymers | VCL, PUF60, JMJD6 | TSHR 4359/4885HPGD 2321/4885ALDH1A1 3595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.