SCHEMBL537953

SCHEMBL537953

C=C[Si](C)(C)OCCCC

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.39
HPGD P15428 1/20 0.39
ALDH1A1 P00352 2/20 0.35
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35
ADRB3 P13945 1/20 0.35
ATM Q13315 1/20 0.32
CYP3A4 P08684 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7931500 0.93 TSHR (0.36) TSHRHPGDALDH1A1
SCHEMBL16543985 0.91 TSHR (0.39) TSHRALDH1A1
SCHEMBL919225 0.91 TSHR (0.39) TSHRALDH1A1
SCHEMBL1260598 0.85
SCHEMBL15302455 0.81 TSHR (0.39) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL198101 0.81 TSHR (0.39) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL2001505 0.80 HPGD (0.32) TSHRHPGD
SCHEMBL29702528 0.80 HPGD (0.32) TSHRHPGD
SCHEMBL6550142 0.78 ADRB2 (0.36) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL1228489 0.78 TSHR (0.40) TSHRHPGDALDH1A1ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9074032-B2 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2015-07-07 US claimed
EP-2414411-B1 MEMBRANES BASED ON POLYVINYL ALCOHOL WACKER CHEMIE AG (DE) 2013-02-20 EP claimed
CN-102875810-A Phenyl-containing MT type resin and preparation method thereof ZHONGHAO CHENGUANG RES INST CHEMICAL INDUSTRY 2013-01-16 CN claimed
US-20120031843-A1 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2012-02-09 US claimed
EP-2414411-A2 MEMBRANES BASED ON POLYVINYL ALCOHOL Wacker Chemie AG (DE) 2012-02-08 EP claimed
WO-2010112372-A2 MEMBRANES BASED ON POLYVINYL ALCOHOL WACKER CHEMIE AG (DE) 2010-10-07 WO claimed
WO-2023225203-A1 SPLIT-PROOF AUTOMOTIVE CORNER MOLDING COMPOUND MCPP INNOVATION LLC (JP) 2023-11-23 WO disclosed
US-20230374285-A1 SPLIT-PROOF AUTOMOTIVE CORNER MOLDING COMPOUND MCPP INNOVATION LLC (JP) 2023-11-23 US disclosed
EP-3666823-B1 THERMOPLASTIC RESIN COMPOSITION FOR WIRE-COATING AND HEAT RESISTANT WIRE RIKEN TECHNOS CORP (JP) 2023-10-25 EP disclosed
CN-112585248-B Sliding material composition, sliding molded article, and sliding member 理研科技株式会社 2023-02-28 CN disclosed
US-11512194-B2 Thermoplastic resin composition for wire-coating and heat resistant wire RIKEN TECHNOS CORPORATION (JP) 2022-11-29 US disclosed
US-11370986-B2 Sliding material composition, sliding molded article, and sliding member RIKEN TECHNOS CORPORATION (JP) 2022-06-28 US disclosed
CN-109790339-B Elastomer composition, water-crosslinkable elastomer composition, and method for producing same 理研科技株式会社 2022-06-14 CN disclosed
US-4767820-A HYDROLYZABLE, PENDANT SILANE MOIETIES ON HOMO- OR COPOLYMER OF AN OLEFIN OR DIOLEFIN UNION CARBIDE CORPORATION (US) 1988-08-30 US disclosed
US-4753993-A WATER CURABLE ETHYLENE POLYMERS HAVING PENDANT HYDROLZABLE SILANE GROUPS UNION CARBIDE CORPORATION (US) 1988-06-28 US disclosed
US-4707520-A Composition based on water-curable thermoplastic polymers and metal carboxylate silanol condensation catalysts UNION CARBIDE CORPORATION (US) 1987-11-17 US disclosed
EP-0212630-A2 Compositions based on water-curable thermoplastic polymers and metal carboxylate silanol condensation catalysts UNION CARBIDE CORPORATION (US) 1987-03-04 EP disclosed
US-4579913-A Composition of a relatively stable polymer of an olefinic monomer and an unsaturated silane, and an organo titanate UNION CARBIDE CORPORATION (US) 1986-04-01 US disclosed
US-4526930-A Contains organotitanate for ester exchange UNION CARBIDE CORPORATION (US) 1985-07-02 US disclosed
EP-0135923-A2 Production of water-curable, silane modified thermoplastic polymers UNION CARBIDE CORPORATION (US) 1985-04-03 EP disclosed