Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL31349237 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2256461 | 0.94 | CA4 (0.60) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL232589 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL222623 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL20604683 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL133559 | 0.86 | — | — | |
| Bicarbonate SCHEMBL121569 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL21951326 | 0.86 | — | — | |
| Bicarbonate SCHEMBL138926 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1908265 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180105475-A1 | NUTRIENT SYSTEM | BIOCARB PTY LTD (AU) | 2018-04-19 | — | — | US | claimed |
| CN-107793261-A | The nano-sized carbon selenium-enriched fertilizer technology of preparing of selenium-rich citrus | 潘月玉 | 2018-03-13 | — | — | CN | claimed |
| JP-10310465-A | — | — | None | — | — | JP | disclosed |
| JP-9291353-A | — | — | None | — | — | JP | disclosed |
| US-20230017197-A1 | RESIN FILM, METHOD FOR PRODUCING RESIN FILM, AND DISPLAY APPARATUS | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2023-01-19 | — | — | US | disclosed |
| CN-112745728-B | Preparation method of water-based micro-nano graphite wind power blade deicing coating system | 西南科技大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-110804309-A | 3D printing polymer powder material and preparation method thereof | 安徽弘泰精密机械科技有限公司 | 2020-02-18 | — | — | CN | disclosed |
| CN-104725628-B | A kind of single functionalization branched polyethylene glycol, preparation method and its bio-related substance containing degradable group | 厦门赛诺邦格生物科技股份有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107711239-A | A kind of cultural method of selenium-rich lichee | 潘月玉 | 2018-02-23 | — | — | CN | disclosed |
| CN-107082687-A | A kind of nano-sized carbon is Se-enriched or mixture fertilizer | 张哲� | 2017-08-22 | — | — | CN | disclosed |
| CN-104725628-A | Single functional branched polyethylene glycol containing degradable radical, preparation method and biorelevant substance of single functional branched polyethylene glycol | XIAMEN SINOPEG BIOTECH CO LTD | 2015-06-24 | — | — | CN | disclosed |
| CN-1929844-A | Muscarinic acetylcholine receptor antagonists | GLAXO GROUP LTD (GB) | 2007-03-14 | — | — | CN | disclosed |
| EP-1711183-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005067537-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-07-28 | — | — | WO | disclosed |
| JP-2000280211-A | MANUFACTURE OF INORGANIC HARDENED COMPOSITION | TOYO CHEM CO LTD | 2000-10-10 | — | — | JP | disclosed |
| JP-H10310465-A | INORGANIC HARDENED COMPOSITION | TOYO CHEM CO LTD | 1998-11-24 | — | — | JP | disclosed |
| JP-H09291353-A | SURFACE COATED END MILL | HITACHI TOOL ENG LTD | 1997-11-11 | — | — | JP | disclosed |
| EP-0514030-B1 | Reagent for detecting occult blood | TABATA KAZUO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5310684-A | Sodium carbonate, B-amino-phthalic acid hydrazide, sodium-iron EDTA, hydrogen peroxide | KAZUO TABATA (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0514030-A1 | Reagent for detecting occult blood | TABATA, Kazuo (JP) | 1992-11-19 | — | — | EP | disclosed |