Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 8/20 | 0.57 |
| ▸ | DRD2 | P14416 | 7/20 | 0.57 |
| ▸ | DRD3 | P35462 | 7/20 | 0.57 |
| ▸ | HTR1B | P28222 | 2/20 | 0.57 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673795 | 0.94 | DRD4 (0.60) | DRD4DRD2DRD3HTR1BHTR1D | |
| SCHEMBL9554727 | 0.89 | MMP3 (0.51) | DRD4DRD2DRD3HTR1BHTR1D | |
| SCHEMBL5207889 | 0.81 | DRD4 (0.53) | DRD4DRD2DRD3L3MBTL1NPC1 | |
| SCHEMBL6678693 | 0.79 | KCNA3 (0.44) | DRD4DRD2DRD3HTR1BHTR1D | |
| SCHEMBL8938905 | 0.76 | DRD4 (0.91) | DRD4DRD2DRD3HTR1BHTR1D | |
| SCHEMBL9330194 | 0.76 | DRD4 (0.62) | DRD4DRD2DRD3HTR1BHTR1D | |
| SCHEMBL2068241 | 0.74 | KCNA3 (0.61) | DRD4DRD2DRD3HTR1BHTR1D | |
| SCHEMBL10476759 | 0.74 | DRD4 (0.95) | DRD4DRD2DRD3HTR1BHTR1D | |
| SCHEMBL11452761 | 0.73 | KCNA3 (0.67) | DRD4DRD2DRD3HTR1BHTR1D | |
| SCHEMBL6343524 | 0.73 | SMN1; SMN2 (0.50) | L3MBTL1SMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152759-B1 | AMINOISOTHIAZOLE COMPOUNDS | BASF Aktiengesellschaft (DE) | 1989-08-23 | — | — | EP | claimed |
| EP-0150034-B1 | DERIVATIVES OF 2-AMINOTHIOPHENE | BASF Aktiengesellschaft (DE) | 1989-08-02 | — | — | EP | claimed |
| US-4785116-A | Aminoisothiazole compounds | BASF AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | claimed |
| EP-2999338-B1 | KNOWN AND NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-07-12 | — | — | EP | disclosed |
| EP-1979354-B1 | DIAZA-SPIRO-[4, 5]-DECANES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-11-11 | — | — | EP | disclosed |
| WO-2004041799-A1 | 5- (SUBSTITUTED PHENYL) -THIADIAZOLIDINE-3-ONES AND THEIR USE AS PTP1B | ASTRAZENECA AB (SE) | 2004-05-21 | — | — | WO | disclosed |
| EP-0152759-B1 | AMINOISOTHIAZOLE COMPOUNDS | BASF Aktiengesellschaft (DE) | 1989-08-23 | — | — | EP | disclosed |
| EP-0150034-B1 | DERIVATIVES OF 2-AMINOTHIOPHENE | BASF Aktiengesellschaft (DE) | 1989-08-02 | — | — | EP | disclosed |
| US-4785116-A | Aminoisothiazole compounds | BASF AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0152759-A1 | Aminoisothiazole compounds | BASF Aktiengesellschaft (DE) | 1985-08-28 | — | — | EP | disclosed |
| EP-0150034-A2 | Derivatives of 2-aminothiophene | BASF Aktiengesellschaft (DE) | 1985-07-31 | — | — | EP | disclosed |
| EP-0150034-A2 | Derivatives of 2-aminothiophene | BASF Aktiengesellschaft (DE) | 1985-07-31 | — | — | EP | disclosed |