Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.53 |
| ▸ | DRD2 | P14416 | 5/20 | 0.53 |
| ▸ | DRD3 | P35462 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | RHOC | P08134 | 1/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3848563 | 0.81 | DRD4 (0.57) | DRD4DRD2DRD3NPC1TAAR1 | |
| SCHEMBL9554727 | 0.79 | MMP3 (0.51) | DRD4DRD2DRD3NPC1RAB9A | |
| SCHEMBL6673795 | 0.76 | DRD4 (0.60) | DRD4DRD2DRD3NPC1RAB9A | |
| SCHEMBL1345118 | 0.75 | MAOB (0.57) | DRD4DRD2DRD3NPC1RAB9A | |
| SCHEMBL2472084 | 0.75 | HTR1B (0.64) | DRD4DRD2DRD3NPC1TAAR1 | |
| SCHEMBL5536815 | 0.75 | ALDH3A1 (0.47) | DRD4DRD2DRD3NPC1RAB9A | |
| SCHEMBL5073531 | 0.74 | DRD4 (0.57) | DRD4DRD2DRD3NPC1TAAR1 | |
| SCHEMBL6849549 | 0.73 | HTR1B (0.66) | DRD4DRD2DRD3NPC1TAAR1 | |
| Hydrochloric Acid SCHEMBL21595631 | 0.73 | HTR1B (0.62) | DRD4DRD2DRD3NPC1TAAR1 | |
| SCHEMBL5540013 | 0.73 | ALDH3A1 (0.50) | DRD4DRD2DRD3RAB9AALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708994-B1 | ARYLOXYALKYLCARBAMATE-TYPE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-08-08 | — | — | EP | disclosed |